Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 80025
Gene Symbol: PANK2
PANK2
Q9BZ23 pantothenate kinase 2 76 0.648 0.379 7.4E-07 0.450 1.000 7 0 2006 2017
Entrez Id: 54902
Gene Symbol: TTC19
TTC19
Q6DKK2 tetratricopeptide repeat domain 19 78 0.659 0.345 1.6E-08 0.420 1.000 3 0 2011 2016
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 265 0.492 0.724 7.3E-03 0.400 0.989 190 5 1998 2018
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha chaperone; membrane traffic protein 176 0.513 0.793 0.90 0.400 1.000 53 3 1999 2018
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.400 0.913 25 0 1994 2016
Entrez Id: 6310
Gene Symbol: ATXN1
ATXN1
P54253 ataxin 1 137 0.550 0.517 0.98 0.400 1.000 17 0 1995 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.400 1.000 16 0 2007 2015
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 calcium-binding protein; hydrolase; protease; signaling molecule 268 0.490 0.690 0.98 0.380 1.000 9 4 2002 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 oxidoreductase 460 0.403 0.862 7.9E-03 0.350 1.000 8 0 2000 2015
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor signaling molecule 264 0.463 0.759 0.20 0.350 1.000 6 0 1998 2014
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor signaling molecule 353 0.426 0.862 0.76 0.350 1.000 6 0 2000 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.350 0.750 6 0 1995 2004
Entrez Id: 2512
Gene Symbol: FTL
FTL
P02792 ferritin light chain storage protein 100 0.582 0.586 1.6E-09 0.340 1.000 5 0 2004 2016
Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
P02511 crystallin alpha B 138 0.546 0.621 2.3E-02 0.340 1.000 5 0 2005 2015
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
O43612 hypocretin neuropeptide precursor 100 0.579 0.724 3.0E-02 0.330 1.000 4 0 2010 2014
Entrez Id: 2056
Gene Symbol: EPO
EPO
P01588 erythropoietin 360 0.425 0.759 1.2E-02 0.320 1.000 3 0 2005 2016
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.310 1.000 4 0 2000 2013
Entrez Id: 9446
Gene Symbol: GSTO1
GSTO1
P78417 glutathione S-transferase omega 1 55 0.627 0.552 3.5E-09 0.310 1.000 2 0 2005 2008
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.310 < 0.001 2 0 2005 2013
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 129 0.545 0.690 3.1E-30 0.300 1.000 15 2 2005 2014
Entrez Id: 5311
Gene Symbol: PKD2
PKD2
Q13563 polycystin 2, transient receptor potential cation channel enzyme modulator; hydrolase; protease; signaling molecule; transporter 95 0.575 0.655 1.9E-04 0.300 1 0 2015 2015
Entrez Id: 6709
Gene Symbol: SPTAN1
SPTAN1
Q13813 spectrin alpha, non-erythrocytic 1 68 0.611 0.552 1.00 0.300 1 0 2015 2015
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
O95263 phosphodiesterase 8B 67 0.672 0.379 1.00 0.300 1 0 2010 2010
Entrez Id: 2495
Gene Symbol: FTH1
FTH1
P02794 ferritin heavy chain 1 storage protein 50 0.627 0.517 0.16 0.300 1 0 2005 2005
Entrez Id: 2948
Gene Symbol: GSTM4
GSTM4
Q03013 glutathione S-transferase mu 4 19 0.727 0.276 1.2E-08 0.300 1 0 2005 2005