Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.700 0.947 78 3 1991 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.600 0.913 25 0 1988 2018
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 361 0.437 0.793 0.15 0.600 1 1 2000 2000
Entrez Id: 6049
Gene Symbol: RNF6
RNF6
Q9Y252 ring finger protein 6 28 0.707 0.310 1.7E-02 0.500 0 0
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 156 0.504 0.655 0.99 0.500 0 0
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1
Q9Y250 leucine zipper tumor suppressor 1 34 0.659 0.379 0.95 0.500 0 0
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member oxidoreductase 236 0.481 0.862 2.5E-09 0.400 1.000 37 1 1996 2017
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide oxidoreductase 152 0.525 0.759 1.1E-06 0.400 1.000 24 1 1998 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 0.850 21 0 1997 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 1.000 16 0 1993 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 1.000 15 0 1994 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 12 0 2000 2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 400 0.407 0.759 0.360 1.000 7 0 2011 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.340 1.000 5 0 2006 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.330 0.333 4 0 1996 2016
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
Q13761 runt related transcription factor 3 nucleic acid binding; transcription factor 168 0.494 0.690 0.96 0.330 1.000 4 0 2007 2017
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
microRNA 145 201 0.476 0.724 0.330 1.000 4 0 2011 2016
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
P50281 matrix metallopeptidase 14 hydrolase; protease 240 0.466 0.724 1.00 0.320 1.000 3 0 2000 2014
Entrez Id: 406985
Gene Symbol: MIR200C
MIR200C
microRNA 200c 114 0.536 0.621 0.320 1.000 2 0 2011 2014
Entrez Id: 50514
Gene Symbol: DEC1
DEC1
Q9P2X7 deleted in esophageal cancer 1 34 0.656 0.414 3.1E-05 0.320 1.000 2 0 2000 2008
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.320 1.000 2 1 2010 2011
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.310 1.000 3 0 2008 2011
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
P04406 glyceraldehyde-3-phosphate dehydrogenase oxidoreductase 188 0.484 0.793 0.11 0.310 1.000 2 0 2005 2006
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase 233 0.475 0.690 1.00 0.310 1.000 2 0 2011 2013
Entrez Id: 11197
Gene Symbol: WIF1
WIF1
Q9Y5W5 WNT inhibitory factor 1 calcium-binding protein 118 0.536 0.586 1.4E-09 0.310 1.000 2 0 2005 2007