Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.922 55 2 1992 2015
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.510 1.000 2 0 2006 2014
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.400 1.000 23 2 2009 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.895 21 0 1995 2012
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.400 1.000 20 2 1992 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 0.929 15 0 1998 2017
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 1.000 15 0 1998 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.400 1.000 14 0 2001 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 1.000 13 0 1992 2012
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 300 0.438 0.759 8.2E-03 0.340 1.000 6 0 1995 2009
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 signaling molecule 437 0.404 0.897 1.9E-02 0.340 1.000 5 0 1999 2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.330 1.000 4 0 2005 2014
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase 328 0.462 0.793 0.89 0.320 1.000 3 0 2007 2013
Entrez Id: 482
Gene Symbol: ATP1B2
ATP1B2
P14415 ATPase Na+/K+ transporting subunit beta 2 transporter 14 0.752 0.207 8.2E-02 0.320 1.000 2 0 2003 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.320 1.000 2 0 2005 2005
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 205 0.477 0.690 0.94 0.310 1.000 2 0 2013 2013
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor signaling molecule 264 0.463 0.759 0.20 0.310 1.000 2 0 2009 2018
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase oxidoreductase 446 0.397 0.828 1.9E-10 0.310 1.000 2 0 2011 2015
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
P36222 chitinase 3 like 1 167 0.502 0.793 8.5E-06 0.310 1.000 2 0 2005 2011
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 enzyme modulator 308 0.458 0.724 1.00 0.310 1.000 2 0 1993 2014
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Q92911 solute carrier family 5 member 5 transporter 157 0.524 0.759 2.9E-03 0.310 1.000 2 0 2003 2015
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D
O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D enzyme modulator; hydrolase; phosphatase 112 0.573 0.724 3.5E-11 0.310 1.000 2 0 2012 2014
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
P08922 ROS proto-oncogene 1, receptor tyrosine kinase 165 0.493 0.759 1.5E-69 0.310 1.000 1 0 2009 2009
Entrez Id: 3925
Gene Symbol: STMN1
STMN1
P16949 stathmin 1 181 0.497 0.793 5.7E-02 0.310 1.000 1 0 2007 2007
Entrez Id: 1181
Gene Symbol: CLCN2
CLCN2
P51788 chloride voltage-gated channel 2 37 0.663 0.379 4.0E-12 0.310 1.000 1 0 2003 2003