Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.915 94 8 1989 2017
Entrez Id: 6910
Gene Symbol: TBX5
TBX5
Q99593 T-box 5 nucleic acid binding; transcription factor 91 0.592 0.586 1.00 0.100 1.000 27 0 1988 2018
Entrez Id: 23291
Gene Symbol: FBXW11
FBXW11
Q9UKB1 F-box and WD repeat domain containing 11 24 0.685 0.310 0.98 0.100 1.000 27 0 1988 2018
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 runt related transcription factor 2 nucleic acid binding; transcription factor 292 0.490 0.621 0.96 0.100 0.960 25 0 2000 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.100 0.960 25 0 1993 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.100 1.000 25 0 1997 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene nucleic acid binding 436 0.396 0.759 1.00 0.100 0.900 20 2 1993 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.100 0.950 20 0 2009 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 enzyme modulator; hydrolase; protease 462 0.391 0.862 0.28 0.100 1.000 18 0 2002 2018
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
P02818 bone gamma-carboxyglutamate protein 117 0.528 0.621 4.6E-08 0.100 0.941 17 0 1994 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.100 0.938 16 0 1997 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.100 1.000 16 0 1999 2016
Entrez Id: 7430
Gene Symbol: EZR
EZR
P15311 ezrin cytoskeletal protein 127 0.533 0.690 0.45 0.100 0.938 16 0 2004 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.100 0.933 15 0 1996 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.100 1.000 14 0 1995 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.100 1.000 14 3 2012 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.100 0.846 13 0 1997 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta kinase; transferase 468 0.389 0.862 1.00 0.100 1.000 13 1 2012 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta kinase; transferase 487 0.386 0.862 1.00 0.100 1.000 13 0 2012 2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma kinase; transferase 490 0.385 0.862 1.5E-06 0.100 1.000 13 0 2012 2017
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 474 0.391 0.897 1.4E-02 0.100 1.000 13 0 2005 2017
Entrez Id: 650
Gene Symbol: BMP2
BMP2
P12643 bone morphogenetic protein 2 signaling molecule 214 0.491 0.759 0.99 0.100 1.000 12 4 1995 2017
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Q6ZT07 TBC1 domain family member 9 enzyme modulator; hydrolase; protease 296 0.434 0.828 2.8E-05 0.100 1.000 12 0 1993 2014
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 0.818 11 0 1996 2016
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 715 0.355 0.828 0.29 0.100 0.909 11 0 1994 2017