| Gene | UniProt | Gene Full Name | Protein Class | N. diseases g | DSI g | DPI g | pLI | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 1213 | 0.320 | 0.923 | 7.9E-04 | 0.030 | None | 0.667 | 3 | 0 | 2013 | 2015 | ||||
|
P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 995 | 0.328 | 0.923 | 6.0E-03 | 0.020 | None | 1.000 | 2 | 0 | 2019 | 2019 | ||||
|
O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 536 | 0.420 | 0.885 | 0.68 | 0.020 | None | 1.000 | 2 | 0 | 2013 | 2014 | ||||
|
P98088 | mucin 5AC, oligomeric mucus/gel-forming | Enzyme modulator | 224 | 0.483 | 0.808 | 1.0E-08 | 0.020 | None | 0.500 | 2 | 0 | 2010 | 2018 | ||||
|
Q5D1E8 | zinc finger CCCH-type containing 12A | Nucleic acid binding | 88 | 0.578 | 0.654 | 0.14 | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||
|
P04637 | tumor protein p53 | Transcription factor | 2494 | 0.236 | 0.962 | 0.53 | 0.010 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||
|
P21439 | ATP binding cassette subfamily B member 4 | Transporter | 157 | 0.529 | 0.615 | 2.2E-07 | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||
|
Q13485 | SMAD family member 4 | Transcription factor | 575 | 0.401 | 0.808 | 1.00 | 0.010 | None | < 0.001 | 1 | 0 | 2018 | 2018 | ||||
|
Cholangitis, primary sclerosing | 67 | 0.603 | 0.731 | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | |||||||
|
P52945 | pancreatic and duodenal homeobox 1 | 185 | 0.530 | 0.654 | 1.8E-02 | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | |||||
|
Q14469 | hes family bHLH transcription factor 1 | Transcription factor | 243 | 0.468 | 0.885 | 0.71 | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||
|
P16104 | H2A.X variant histone | Nucleic acid binding | 212 | 0.484 | 0.808 | 0.18 | 0.010 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||
|
P35556 | fibrillin 2 | Calcium-binding protein | 211 | 0.505 | 0.808 | 1.00 | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
Q14457 | beclin 1 | Enzyme modulator | 373 | 0.432 | 0.846 | 0.94 | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 |