|
| Entrez Id: |
3265 |
| Gene Symbol: |
HRAS |
HRAS
|
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
698
|
0.378 |
0.885 |
8.0E-02 |
1.000 |
definitive
|
0.974 |
115
|
18
|
1982 |
2020 |
|
| Entrez Id: |
3845 |
| Gene Symbol: |
KRAS |
KRAS
|
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
1213
|
0.320 |
0.923 |
7.9E-04 |
0.600 |
disputed
|
1.000 |
12
|
1
|
2006 |
2018 |
|
| Entrez Id: |
5781 |
| Gene Symbol: |
PTPN11 |
PTPN11
|
Q06124
|
protein tyrosine phosphatase non-receptor type 11
|
|
702
|
0.385 |
0.923 |
1.00 |
0.550 |
disputed
|
1.000 |
6
|
0
|
2003 |
2016 |
|
| Entrez Id: |
5604 |
| Gene Symbol: |
MAP2K1 |
MAP2K1
|
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
389
|
0.439 |
0.846 |
0.90 |
0.550 |
disputed
|
1.000 |
6
|
0
|
2007 |
2016 |
|
| Entrez Id: |
673 |
| Gene Symbol: |
BRAF |
BRAF
|
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1228
|
0.319 |
0.846 |
1.00 |
0.540 |
disputed
|
1.000 |
6
|
0
|
2006 |
2016 |
|
| Entrez Id: |
5605 |
| Gene Symbol: |
MAP2K2 |
MAP2K2
|
P36507
|
mitogen-activated protein kinase kinase 2
|
Kinase
|
177
|
0.534 |
0.731 |
0.97 |
0.540 |
|
1.000 |
5
|
0
|
2007 |
2016 |
|
| Entrez Id: |
5894 |
| Gene Symbol: |
RAF1 |
RAF1
|
P04049
|
Raf-1 proto-oncogene, serine/threonine kinase
|
Kinase
|
470
|
0.418 |
0.885 |
0.85 |
0.320 |
disputed
|
1.000 |
3
|
0
|
2008 |
2011 |
|
| Entrez Id: |
8036 |
| Gene Symbol: |
SHOC2 |
SHOC2
|
Q9UQ13
|
SHOC2 leucine rich repeat scaffold protein
|
|
97
|
0.593 |
0.769 |
1.00 |
0.310 |
disputed
|
1.000 |
2
|
0
|
2010 |
2011 |
|
| Entrez Id: |
6654 |
| Gene Symbol: |
SOS1 |
SOS1
|
Q07889
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
Enzyme modulator
|
261
|
0.485 |
0.808 |
1.00 |
0.310 |
disputed
|
1.000 |
2
|
0
|
2010 |
2011 |
|
| Entrez Id: |
5921 |
| Gene Symbol: |
RASA1 |
RASA1
|
P20936
|
RAS p21 protein activator 1
|
Enzyme modulator
|
237
|
0.481 |
0.885 |
1.00 |
0.310 |
|
1.000 |
1
|
2
|
2010 |
2010 |
|
| Entrez Id: |
4893 |
| Gene Symbol: |
NRAS |
NRAS
|
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
611
|
0.390 |
0.808 |
0.49 |
0.300 |
limited
|
1.000 |
2
|
0
|
2013 |
2017 |
|
| Entrez Id: |
22808 |
| Gene Symbol: |
MRAS |
MRAS
|
O14807
|
muscle RAS oncogene homolog
|
Enzyme modulator
|
113
|
0.590 |
0.731 |
0.92 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
5922 |
| Gene Symbol: |
RASA2 |
RASA2
|
Q15283
|
RAS p21 protein activator 2
|
Enzyme modulator
|
116
|
0.579 |
0.769 |
7.4E-31 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
6016 |
| Gene Symbol: |
RIT1 |
RIT1
|
Q92963
|
Ras like without CAAX 1
|
Enzyme modulator
|
184
|
0.527 |
0.808 |
0.13 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
6237 |
| Gene Symbol: |
RRAS |
RRAS
|
P10301
|
RAS related
|
Enzyme modulator
|
149
|
0.543 |
0.808 |
4.7E-03 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
5500 |
| Gene Symbol: |
PPP1CB |
PPP1CB
|
P62140
|
protein phosphatase 1 catalytic subunit beta
|
Enzyme
|
105
|
0.601 |
0.577 |
1.00 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
6655 |
| Gene Symbol: |
SOS2 |
SOS2
|
Q07890
|
SOS Ras/Rho guanine nucleotide exchange factor 2
|
Enzyme modulator
|
92
|
0.608 |
0.692 |
1.00 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
144568 |
| Gene Symbol: |
A2ML1 |
A2ML1
|
A8K2U0
|
alpha-2-macroglobulin like 1
|
Enzyme modulator
|
94
|
0.590 |
0.692 |
1.6E-34 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
8216 |
| Gene Symbol: |
LZTR1 |
LZTR1
|
Q8N653
|
leucine zipper like transcription regulator 1
|
|
152
|
0.547 |
0.808 |
1.0E-92 |
0.300 |
|
|
0
|
0
|
|
|
|
| Entrez Id: |
2006 |
| Gene Symbol: |
ELN |
ELN
|
P15502
|
elastin
|
|
545
|
0.415 |
0.885 |
2.1E-14 |
0.050 |
None
|
1.000 |
5
|
1
|
1996 |
2011 |
|
| Entrez Id: |
5609 |
| Gene Symbol: |
MAP2K7 |
MAP2K7
|
O14733
|
mitogen-activated protein kinase kinase 7
|
Kinase
|
408
|
0.419 |
0.808 |
1.00 |
0.020 |
None
|
1.000 |
2
|
0
|
2007 |
2009 |
|
| Entrez Id: |
5594 |
| Gene Symbol: |
MAPK1 |
MAPK1
|
P28482
|
mitogen-activated protein kinase 1
|
Kinase
|
1059
|
0.330 |
0.923 |
1.00 |
0.010 |
None
|
1.000 |
1
|
0
|
2009 |
2009 |
|
| Entrez Id: |
9628 |
| Gene Symbol: |
RGS6 |
RGS6
|
P49758
|
regulator of G protein signaling 6
|
|
117
|
0.564 |
0.769 |
0.44 |
0.010 |
None
|
1.000 |
1
|
0
|
2010 |
2010 |
|
| Entrez Id: |
5291 |
| Gene Symbol: |
PIK3CB |
PIK3CB
|
P42338
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
|
Kinase
|
1083
|
0.322 |
0.885 |
1.00 |
0.010 |
None
|
1.000 |
1
|
0
|
2015 |
2015 |
|
| Entrez Id: |
7157 |
| Gene Symbol: |
TP53 |
TP53
|
P04637
|
tumor protein p53
|
Transcription factor
|
2494
|
0.236 |
0.962 |
0.53 |
0.010 |
None
|
1.000 |
1
|
0
|
2015 |
2015 |