Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.700 0.960 129 4 1983 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.700 1.000 34 11 2002 2018
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18
Q96BI1 solute carrier family 22 member 18 50 0.621 0.483 6.0E-06 0.600 1 1 1998 1998
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 0.977 691 9 1988 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.500 0.971 35 2 2002 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 transcription factor 475 0.419 0.759 1.00 0.490 1.000 12 4 2000 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.450 0.800 7 3 2000 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.960 400 25 1989 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 0.969 65 2 1989 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 1.000 25 1 1998 2017
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit nucleic acid binding 276 0.463 0.724 2.1E-07 0.400 0.900 20 6 2005 2016
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
Q16620 neurotrophic receptor tyrosine kinase 2 165 0.514 0.586 1.00 0.330 1.000 3 0 2013 2017
Entrez Id: 2042
Gene Symbol: EPHA3
EPHA3
P29320 EPH receptor A3 95 0.552 0.586 1.4E-05 0.320 1.000 3 1 2006 2016
Entrez Id: 4916
Gene Symbol: NTRK3
NTRK3
Q16288 neurotrophic receptor tyrosine kinase 3 102 0.547 0.586 1.00 0.310 1.000 1 0 2017 2017
Entrez Id: 253260
Gene Symbol: RICTOR
RICTOR
Q6R327 RPTOR independent companion of MTOR complex 2 39 0.656 0.379 1.00 0.310 1.000 1 0 2016 2016
Entrez Id: 283106
Gene Symbol: CSNK2A3
CSNK2A3
Q8NEV1 casein kinase 2 alpha 3 5 0.834 0.069 2.7E-10 0.310 1.000 1 1 2010 2010
Entrez Id: 25878
Gene Symbol: MXRA5
MXRA5
Q9NR99 matrix remodeling associated 5 5 0.857 0.069 3.0E-02 0.300 1 2 2012 2012
Entrez Id: 894
Gene Symbol: CCND2
CCND2
P30279 cyclin D2 enzyme modulator 158 0.519 0.655 0.99 0.300 0 0
Entrez Id: 5885
Gene Symbol: RAD21
RAD21
O60216 RAD21 cohesin complex component 145 0.559 0.759 1.00 0.300 0 0
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
Q92963 Ras like without CAAX 1 enzyme modulator 113 0.619 0.621 0.15 0.300 0 0
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.200 0.976 48 10 2002 2017
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit receptor; transporter 84 0.584 0.448 1.2E-07 0.200 1.000 45 14 2008 2017
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit receptor; transporter 81 0.598 0.414 1.8E-06 0.200 0.950 41 9 2008 2016
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit nucleic acid binding 362 0.447 0.828 1.7E-20 0.200 0.897 40 2 2001 2014
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like lyase 60 0.602 0.517 5.7E-05 0.200 0.957 27 7 2008 2017