Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.700 0.968 68 5 2002 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.600 0.986 80 16 1994 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 nucleic acid binding 320 0.437 0.690 0.91 0.600 0.966 32 10 1995 2018
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 189 0.495 0.586 2.2E-05 0.600 1.000 31 33 1998 2013
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.500 0.946 93 3 1991 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.500 1.000 48 8 2000 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.500 0.977 44 7 1998 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.500 1.000 21 2 1997 2014
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase hydrolase; nucleic acid binding 99 0.551 0.621 2.7E-17 0.460 1.000 30 10 1993 2015
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ
Q12913 protein tyrosine phosphatase, receptor type J hydrolase; phosphatase 47 0.636 0.379 7.8E-12 0.450 1.000 5 3 2002 2010
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12
Q05209 protein tyrosine phosphatase, non-receptor type 12 32 0.681 0.552 1.00 0.420 1.000 2 1 1994 2014
Entrez Id: 25788
Gene Symbol: RAD54B
RAD54B
O95073 Q9Y620 RAD54 homolog B 23 0.701 0.345 4.8E-13 0.420 1.000 2 1 1999 2002
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 361 0.437 0.793 0.15 0.400 1.000 13 0 1995 2018
Entrez Id: 5157
Gene Symbol: PDGFRL
PDGFRL
Q15198 platelet derived growth factor receptor like kinase; receptor; transferase 14 0.762 0.310 6.5E-15 0.400 1 1 1995 1995
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 222 0.473 0.690 6.7E-15 0.380 1.000 8 0 1998 2016
Entrez Id: 6714
Gene Symbol: SRC
SRC
P12931 SRC proto-oncogene, non-receptor tyrosine kinase 177 0.502 0.690 1.00 0.380 0.625 8 1 1999 2015
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component nucleic acid binding 154 0.526 0.586 1.2E-27 0.370 1.000 7 0 2011 2016
Entrez Id: 4512
Gene Symbol: COX1
COX1
P00395 cytochrome c oxidase subunit I oxidoreductase 228 0.494 0.862 0.330 1.000 5 2 2000 2010
Entrez Id: 4149
Gene Symbol: MAX
MAX
P61244 MYC associated factor X nucleic acid binding; transcription factor 84 0.604 0.586 0.85 0.310 1.000 1 0 1996 1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.200 0.961 234 6 1991 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.200 1.000 24 1 2005 2018
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator signaling molecule 267 0.450 0.862 0.30 0.190 1.000 10 2 1997 2014
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 156 0.504 0.655 0.99 0.170 0.857 8 1 1992 2017
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase enzyme modulator 477 0.420 0.690 0.53 0.140 1.000 6 3 1987 2017
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 91 0.570 0.552 0.66 0.140 1.000 5 2 2000 2013