Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.400 None 0.978 90 4 2003 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 1.000 44 2 1998 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.400 None 1.000 11 0 1998 2020
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.400 None 1.000 11 4 2005 2018
Entrez Id: 6714
Gene Symbol: SRC
SRC
P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 265 0.467 0.885 1.00 0.400 None 0.700 10 1 1999 2018
Entrez Id: 5795
Gene Symbol: PTPRJ
PTPRJ
Q12913 protein tyrosine phosphatase receptor type J Enzyme 79 0.606 0.615 1.3E-11 0.350 None 1.000 5 1 2002 2010
Entrez Id: 25788
Gene Symbol: RAD54B
RAD54B
O95073 Q9Y620 RAD54 homolog B 38 0.659 0.462 8.1E-13 0.320 None 1.000 2 0 1999 2002
Entrez Id: 4149
Gene Symbol: MAX
MAX
P61244 MYC associated factor X Transcription factor 141 0.553 0.769 0.83 0.310 None 1.000 1 0 1996 1996
Entrez Id: 5782
Gene Symbol: PTPN12
PTPN12
Q05209 protein tyrosine phosphatase non-receptor type 12 48 0.641 0.769 1.00 0.310 None 1.000 1 0 2018 2018
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.220 None 1.000 3 0 1991 2015
Entrez Id: 6372
Gene Symbol: CXCL6
CXCL6
P80162 C-X-C motif chemokine ligand 6 Signaling 90 0.582 0.692 2.7E-09 0.210 None 1.000 2 0 2008 2017
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
P14222 perforin 1 163 0.540 0.692 5.5E-06 0.200 None 1.000 1 0 2012 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.972 247 6 1991 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.100 None 0.995 194 0 1995 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 0.985 135 5 1983 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 0.948 116 1 1996 2019
Entrez Id: 168400
Gene Symbol: DDX53
DDX53
Q86TM3 DEAD-box helicase 53 117 0.568 0.846 0.66 0.100 None 1.000 107 0 1997 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.980 102 5 1989 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.989 93 0 1976 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.967 90 3 1995 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.976 83 7 1994 2020
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.100 None 0.936 78 6 1992 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 69 1 2000 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.985 65 2 1989 2019
Entrez Id: 1738
Gene Symbol: DLD
DLD
P09622 dihydrolipoamide dehydrogenase Enzyme 190 0.517 0.769 9.5E-03 0.100 None 0.949 59 1 1981 2019