Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.700 0.973 297 2 1986 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.700 0.941 169 2 1994 2018
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.700 1.000 23 3 1992 2018
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
P10914 interferon regulatory factor 1 nucleic acid binding; transcription factor 165 0.503 0.724 0.99 0.640 1.000 5 3 1998 2017
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase hydrolase; nucleic acid binding 99 0.551 0.621 2.7E-17 0.640 1.000 5 4 2004 2016
Entrez Id: 843
Gene Symbol: CASP10
CASP10
Q92851 caspase 10 enzyme modulator; hydrolase; protease 102 0.561 0.517 5.2E-12 0.630 1.000 3 1 2002 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.500 1.000 69 0 2003 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 665 0.398 0.759 1.00 0.500 1.000 40 1 1993 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.500 0.931 31 6 1987 2017
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
Q99612 Kruppel like factor 6 nucleic acid binding; transcription factor 125 0.534 0.690 0.98 0.460 0.833 6 1 2005 2012
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 1.000 56 2 1989 2018
Entrez Id: 7031
Gene Symbol: TFF1
TFF1
P04155 trefoil factor 1 signaling molecule 106 0.542 0.655 9.2E-04 0.400 1.000 32 0 1990 2016
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.400 1.000 15 0 1998 2018
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 222 0.473 0.690 6.7E-15 0.380 1.000 8 0 2003 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.360 0.667 6 0 2003 2013
Entrez Id: 84260
Gene Symbol: TCHP
TCHP
Q9BT92 trichoplein keratin filament binding 124 0.520 0.759 2.5E-16 0.330 1.000 4 1 2009 2016
Entrez Id: 545
Gene Symbol: ATR
ATR
Q13535 ATR serine/threonine kinase kinase; nucleic acid binding; transferase 255 0.486 0.759 1.7E-08 0.320 1.000 2 0 2000 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.320 1.000 2 1 1998 2005
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 66 0.616 0.345 1.8E-25 0.310 1.000 1 0 2013 2013
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 91 0.570 0.552 0.66 0.310 1.000 1 0 2008 2008
Entrez Id: 51366
Gene Symbol: UBR5
UBR5
O95071 ubiquitin protein ligase E3 component n-recognin 5 32 0.667 0.483 1.00 0.310 1.000 1 0 2006 2006
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 62 0.604 0.517 0.17 0.200 1.000 32 4 2008 2017
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 336 0.429 0.828 9.3E-02 0.200 0.963 30 2 1998 2018
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
Q13131 protein kinase AMP-activated catalytic subunit alpha 1 kinase; transferase 119 0.540 0.621 0.11 0.200 1.000 12 5 2012 2018
Entrez Id: 51196
Gene Symbol: PLCE1
PLCE1
Q9P212 phospholipase C epsilon 1 calcium-binding protein; enzyme modulator; hydrolase; signaling molecule 70 0.616 0.517 4.2E-10 0.190 1.000 9 4 2010 2016