Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.700 1.000 36 3 1983 2016
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 558 0.417 0.759 1.8E-05 0.500 0.926 69 7 2001 2018
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 457 0.403 0.759 1.00 0.400 0.935 31 0 1993 2016
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit nucleic acid binding 362 0.447 0.828 1.7E-20 0.400 0.917 12 2 2001 2014
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.360 1.000 6 0 2008 2017
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.340 1.000 4 0 2009 2016
Entrez Id: 10735
Gene Symbol: STAG2
STAG2
Q8N3U4 stromal antigen 2 nucleic acid binding 34 0.672 0.310 1.00 0.340 0.750 4 0 2014 2018
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A transcription factor 175 0.543 0.724 1.00 0.330 1.000 3 0 2011 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 222 0.473 0.690 6.7E-15 0.310 1.000 1 0 2015 2015
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4, p53 regulator nucleic acid binding 159 0.501 0.724 1.00 0.310 1.000 1 0 2015 2015
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.310 1.000 1 0 2017 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 nucleic acid binding; transcription factor 264 0.467 0.828 1.00 0.310 1.000 1 0 1989 1989
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4
P54764 EPH receptor A4 68 0.609 0.586 1.00 0.300 1 1 2007 2007
Entrez Id: 7273
Gene Symbol: TTN
TTN
Q8WZ42 titin 159 0.534 0.655 6.4E-84 0.300 1 1 2007 2007
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
Q00597 FA complementation group C 120 0.569 0.655 2.6E-13 0.300 0 0
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.300 0 0
Entrez Id: 79718
Gene Symbol: TBL1XR1
TBL1XR1
Q9BZK7 transducin beta like 1 X-linked receptor 1 155 0.567 0.690 1.00 0.300 0 0
Entrez Id: 79834
Gene Symbol: PEAK1
PEAK1
Q9H792 pseudopodium enriched atypical kinase 1 11 0.785 0.207 1.0E-03 0.300 0 0
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 62 0.604 0.517 0.17 0.200 1.000 13 2 2001 2016
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
Q9Y6A5 transforming acidic coiled-coil containing protein 3 22 0.707 0.345 3.3E-07 0.150 1.000 7 1 2010 2018
Entrez Id: 6563
Gene Symbol: SLC14A1
SLC14A1
Q13336 solute carrier family 14 member 1 (Kidd blood group) 15 0.743 0.379 1.1E-13 0.140 1.000 5 3 2012 2015
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 56 0.639 0.483 1.5E-02 0.110 1.000 2 1 2008 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.981 162 4 1991 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.100 1.000 57 1 1993 2017
Entrez Id: 10
Gene Symbol: NAT2
NAT2
P11245 N-acetyltransferase 2 transferase 228 0.466 0.828 4.1E-06 0.100 0.964 55 0 1996 2017