Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
P04198 MYCN proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 232 0.481 0.759 0.89 0.100 0.955 554 0 1985 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.932 117 4 1988 2016
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase 274 0.448 0.724 3.5E-06 0.100 0.925 93 5 2000 2018
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.100 0.983 58 4 1989 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 0.955 44 0 1992 2016
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 203 0.498 0.759 2.5E-06 0.100 0.951 41 0 1989 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor signaling molecule 591 0.382 0.828 0.70 0.100 0.975 40 0 1993 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.100 1.000 35 0 1985 2018
Entrez Id: 8929
Gene Symbol: PHOX2B
PHOX2B
Q99453 paired like homeobox 2b 103 0.611 0.483 0.94 0.100 0.943 35 1 2004 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.100 0.941 34 1 2000 2015
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor signaling molecule 353 0.426 0.862 0.76 0.100 0.969 32 0 1989 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.100 0.969 32 0 2000 2017
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
P04629 neurotrophic receptor tyrosine kinase 1 306 0.443 0.759 6.8E-06 0.100 1.000 30 1 1993 2013
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene 452 0.418 0.724 1.00 0.100 0.929 28 0 1990 2016
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 457 0.403 0.759 1.00 0.100 1.000 28 1 1994 2011
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene nucleic acid binding 436 0.396 0.759 1.00 0.100 0.889 27 0 1995 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 oxidoreductase 456 0.406 0.931 0.13 0.100 1.000 27 5 1988 2013
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.100 0.958 24 0 1989 2014
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
P08138 nerve growth factor receptor receptor 160 0.508 0.724 0.30 0.100 1.000 21 0 1987 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.100 0.952 21 0 2003 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 enzyme modulator; hydrolase; protease 462 0.391 0.862 0.28 0.100 0.900 20 0 2000 2015
Entrez Id: 7161
Gene Symbol: TP73
TP73
O15350 tumor protein p73 transcription factor 213 0.472 0.724 1.00 0.100 1.000 20 1 1997 2016
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.100 1.000 19 0 1991 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta kinase; transferase 487 0.386 0.862 1.00 0.100 0.947 19 0 2003 2016
Entrez Id: 83478
Gene Symbol: ARHGAP24
ARHGAP24
Q8N264 Rho GTPase activating protein 24 188 0.481 0.724 6.1E-10 0.100 1.000 19 2 1997 2016