Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5428
Gene Symbol: POLG
POLG 		P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.500 None 0.957 46 8 2003 2020
Entrez Id: 26291
Gene Symbol: FGF21
FGF21 		Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.100 None 0.882 17 0 2012 2019
Entrez Id: 9518
Gene Symbol: GDF15
GDF15 		Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.100 None 0.900 10 0 2015 2020
Entrez Id: 2395
Gene Symbol: FXN
FXN 		Q16595 frataxin Enzyme 220 0.510 0.654 0.34 0.090 None 1.000 9 0 1997 2020
Entrez Id: 4508
Gene Symbol: ATP6
ATP6 		P00846 ATP synthase F0 subunit 6 Transporter 226 0.541 0.731 0.180 None 0.875 8 5 1998 2019
Entrez Id: 56652
Gene Symbol: TWNK
TWNK 		Q96RR1 twinkle mtDNA helicase Enzyme 245 0.516 0.692 3.2E-03 0.170 None 1.000 8 7 2010 2017
Entrez Id: 4567
Gene Symbol: TRNL1
TRNL1 		tRNA 234 0.534 0.731 0.150 None 1.000 7 1 2001 2019
Entrez Id: 4976
Gene Symbol: OPA1
OPA1 		O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 236 0.510 0.846 0.99 0.150 None 0.833 6 6 2002 2020
Entrez Id: 50484
Gene Symbol: RRM2B
RRM2B 		Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 238 0.527 0.769 2.4E-03 0.150 None 1.000 6 2 2007 2019
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.340 None 1.000 5 0 2012 2019
Entrez Id: 4576
Gene Symbol: TRNT
TRNT 		tRNA 36 0.729 0.538 0.110 None 1.000 5 1 1993 2018
Entrez Id: 1890
Gene Symbol: TYMP
TYMP 		P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.050 None 1.000 5 0 1999 2018
Entrez Id: 57132
Gene Symbol: CHMP1B
CHMP1B 		Q7LBR1 charged multivesicular body protein 1B Transporter 24 0.736 0.462 0.73 0.050 None 1.000 5 0 2010 2014
Entrez Id: 51067
Gene Symbol: YARS2
YARS2 		Q9Y2Z4 tyrosyl-tRNA synthetase 2 Enzyme 55 0.663 0.462 3.0E-11 0.130 None 1.000 4 2 2014 2017
Entrez Id: 7035
Gene Symbol: TFPI
TFPI 		P10646 tissue factor pathway inhibitor Enzyme modulator 230 0.486 0.808 0.25 0.040 None 1.000 4 0 2012 2019
Entrez Id: 9377
Gene Symbol: COX5A
COX5A 		P20674 cytochrome c oxidase subunit 5A Enzyme 171 0.515 0.846 0.49 0.040 None 1.000 4 0 1997 2014
Entrez Id: 1351
Gene Symbol: COX8A
COX8A 		P10176 cytochrome c oxidase subunit 8A Enzyme 526 0.400 0.846 0.12 0.040 None 1.000 4 0 1997 2014
Entrez Id: 1371
Gene Symbol: CPOX
CPOX 		P36551 coproporphyrinogen oxidase Enzyme 246 0.488 0.846 0.17 0.040 None 1.000 4 0 1997 2014
Entrez Id: 291
Gene Symbol: SLC25A4
SLC25A4 		P12235 solute carrier family 25 member 4 Transporter 160 0.568 0.692 0.45 0.140 None 1.000 4 2 2000 2018
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.040 None 1.000 4 0 2009 2019
Entrez Id: 57176
Gene Symbol: VARS2
VARS2 		Q5ST30 valyl-tRNA synthetase 2, mitochondrial 37 0.666 0.577 5.8E-17 0.040 None 1.000 4 0 2014 2019
Entrez Id: 4537
Gene Symbol: ND3
ND3 		P03897 NADH dehydrogenase, subunit 3 (complex I) 113 0.604 0.654 0.030 None 1.000 3 4 2009 2017
Entrez Id: 54802
Gene Symbol: TRIT1
TRIT1 		Q9H3H1 tRNA isopentenyltransferase 1 Enzyme 73 0.621 0.692 4.1E-11 0.030 None 1.000 3 0 2017 2019
Entrez Id: 7084
Gene Symbol: TK2
TK2 		O00142 thymidine kinase 2 Kinase 143 0.585 0.615 3.9E-07 0.030 None 1.000 3 0 2008 2016
Entrez Id: 1757
Gene Symbol: SARDH
SARDH 		Q9UL12 sarcosine dehydrogenase Enzyme 166 0.523 0.846 5.3E-16 0.030 None 1.000 3 0 2012 2017