Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit nucleic acid binding; transferase 348 0.477 0.724 1.3E-09 0.700 strong 0.943 39 9 1993 2018
Entrez Id: 92667
Gene Symbol: MGME1
MGME1
Q9BQP7 mitochondrial genome maintenance exonuclease 1 38 0.735 0.345 1.7E-03 0.520 strong 1.000 2 0 2013 2015
Entrez Id: 80224
Gene Symbol: NUBPL
NUBPL
Q8TB37 nucleotide binding protein like 74 0.648 0.414 1.0E-05 0.510 strong 1.000 2 0 2010 2014
Entrez Id: 55572
Gene Symbol: FOXRED1
FOXRED1
Q96CU9 FAD dependent oxidoreductase domain containing 1 oxidoreductase 92 0.616 0.448 5.1E-14 0.510 strong 1.000 2 1 2010 2011
Entrez Id: 6341
Gene Symbol: SCO1
SCO1
O75880 SCO1, cytochrome c oxidase assembly protein oxidoreductase 74 0.645 0.621 2.3E-04 0.510 strong 1.000 2 0 2007 2011
Entrez Id: 4358
Gene Symbol: MPV17
MPV17
P39210 MPV17, mitochondrial inner membrane protein transmembrane receptor regulatory/adaptor protein 104 0.611 0.483 1.2E-10 0.500 strong 1 0 2009 2009
Entrez Id: 7386
Gene Symbol: UQCRFS1
UQCRFS1
P47985 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 42 0.639 0.345 0.53 0.500 limited 0 0
Entrez Id: 56652
Gene Symbol: TWNK
TWNK
Q96RR1 twinkle mtDNA helicase nucleic acid binding 142 0.567 0.517 0.450 strong 1.000 6 4 2010 2017
Entrez Id: 50484
Gene Symbol: RRM2B
RRM2B
Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B oxidoreductase 169 0.554 0.655 2.8E-03 0.440 strong 1.000 5 2 2007 2017
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
O60313 OPA1, mitochondrial dynamin like GTPase cytoskeletal protein; enzyme modulator; hydrolase 150 0.555 0.621 1.00 0.430 strong 1.000 4 4 2002 2017
Entrez Id: 291
Gene Symbol: SLC25A4
SLC25A4
P12235 solute carrier family 25 member 4 68 0.627 0.552 0.49 0.420 strong 1.000 3 2 2000 2017
Entrez Id: 2671
Gene Symbol: GFER
GFER
P55789 growth factor, augmenter of liver regeneration oxidoreductase 58 0.619 0.655 2.1E-04 0.410 strong 1.000 3 2 2009 2017
Entrez Id: 51067
Gene Symbol: YARS2
YARS2
Q9Y2Z4 tyrosyl-tRNA synthetase 2 ligase; nucleic acid binding 63 0.690 0.379 4.8E-11 0.410 strong 1.000 2 1 2015 2017
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
Q9UQ90 SPG7, paraplegin matrix AAA peptidase subunit hydrolase; protease 142 0.542 0.655 3.3E-35 0.410 strong 1.000 2 2 1999 2017
Entrez Id: 55005
Gene Symbol: RMND1
RMND1
Q9NWS8 required for meiotic nuclear division 1 homolog 55 0.696 0.345 4.2E-10 0.400 strong 1 9 2016 2016
Entrez Id: 55863
Gene Symbol: TMEM126B
TMEM126B
Q8IUX1 transmembrane protein 126B 64 0.676 0.379 1.2E-03 0.400 strong 1 2 2017 2017
Entrez Id: 84340
Gene Symbol: GFM2
GFM2
Q969S9 G elongation factor mitochondrial 2 enzyme modulator; hydrolase; nucleic acid binding 1 4.2E-19 0.400 strong 1 2 2017 2017
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 SCO2, cytochrome c oxidase assembly protein oxidoreductase 63 0.648 0.414 6.8E-07 0.350 strong 1.000 5 0 2000 2014
Entrez Id: 2395
Gene Symbol: FXN
FXN
Q16595 frataxin kinase; transferase; transporter 162 0.527 0.586 0.33 0.350 strong 1.000 5 0 1997 2012
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase transferase 207 0.513 0.655 7.2E-05 0.340 strong 1.000 4 0 1999 2015
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
P10176 cytochrome c oxidase subunit 8A oxidoreductase 241 0.461 0.793 0.11 0.330 strong 1.000 4 0 1997 2016
Entrez Id: 6834
Gene Symbol: SURF1
SURF1
Q15526 SURF1, cytochrome c oxidase assembly factor oxidoreductase 92 0.596 0.483 2.2E-13 0.330 strong 1.000 3 0 1999 2013
Entrez Id: 9377
Gene Symbol: COX5A
COX5A
P20674 cytochrome c oxidase subunit 5A oxidoreductase 75 0.580 0.655 0.51 0.330 limited 1.000 3 0 1997 2014
Entrez Id: 79133
Gene Symbol: NDUFAF5
NDUFAF5
Q5TEU4 NADH:ubiquinone oxidoreductase complex assembly factor 5 73 0.645 0.379 5.3E-10 0.320 strong 1.000 3 0 2008 2013
Entrez Id: 54968
Gene Symbol: TMEM70
TMEM70
Q9BUB7 transmembrane protein 70 91 0.656 0.586 1.7E-02 0.320 strong 1.000 2 0 2010 2015