Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 10381
Gene Symbol: TUBB3
TUBB3
Q13509 tubulin beta 3 class III Cellular structure 259 0.486 0.808 2.6E-10 0.370 None 1.000 7 0 2008 2019
Entrez Id: 23213
Gene Symbol: SULF1
SULF1
Q8IWU6 sulfatase 1 Enzyme 83 0.585 0.538 1.4E-03 0.370 None 1.000 7 0 2007 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.360 None 1.000 7 0 2010 2017
Entrez Id: 331
Gene Symbol: XIAP
XIAP
P98170 X-linked inhibitor of apoptosis Enzyme modulator 321 0.447 0.808 0.92 0.360 None 0.857 7 0 2003 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.360 None 0.857 7 1 1999 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.360 None 1.000 7 0 2000 2019
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.360 None 1.000 6 1 2001 2015
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.360 None 1.000 6 5 1994 2019
Entrez Id: 7476
Gene Symbol: WNT7A
WNT7A
O00755 Wnt family member 7A Signaling 182 0.531 0.692 3.6E-02 0.350 None 1.000 5 0 2009 2017
Entrez Id: 2122
Gene Symbol: MECOM
MECOM
Q03112 MDS1 and EVI1 complex locus 191 0.513 0.731 1.00 0.340 None 1.000 5 0 1996 2013
Entrez Id: 374
Gene Symbol: AREG
AREG
P15514 amphiregulin Signaling 221 0.487 0.769 0.35 0.340 None 1.000 5 0 2002 2017
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.340 None 1.000 5 0 1997 2013
Entrez Id: 6502
Gene Symbol: SKP2
SKP2
Q13309 S-phase kinase associated protein 2 204 0.492 0.808 0.96 0.340 None 1.000 5 0 2009 2019
Entrez Id: 1801
Gene Symbol: DPH1
DPH1
Q9BZG8 diphthamide biosynthesis 1 51 0.653 0.538 8.0E-17 0.340 None 1.000 4 2 1999 2017
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.340 None 1.000 4 0 1999 2017
Entrez Id: 5655
Gene Symbol: KLK10
KLK10
O43240 kallikrein related peptidase 10 Enzyme 70 0.608 0.538 4.4E-07 0.340 None 1.000 4 0 2003 2013
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.330 None 1.000 7 0 2005 2018
Entrez Id: 10013
Gene Symbol: HDAC6
HDAC6
Q9UBN7 histone deacetylase 6 Epigenetic regulator 288 0.465 0.846 1.00 0.330 None 1.000 4 0 2008 2019
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
P24522 growth arrest and DNA damage inducible alpha 151 0.526 0.769 4.4E-02 0.330 None 1.000 4 0 2000 2015
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Q92911 solute carrier family 5 member 5 Transporter 195 0.499 0.769 2.9E-03 0.330 None 0.750 4 0 2003 2018
Entrez Id: 7158
Gene Symbol: TP53BP1
TP53BP1
Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 158 0.520 0.731 1.00 0.330 None 1.000 4 0 2013 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.330 None 1.000 4 0 1994 2014
Entrez Id: 2246
Gene Symbol: FGF1
FGF1
P05230 fibroblast growth factor 1 Signaling 184 0.507 0.846 0.44 0.330 None 1.000 3 1 2014 2017
Entrez Id: 51755
Gene Symbol: CDK12
CDK12
Q9NYV4 cyclin dependent kinase 12 Kinase 54 0.638 0.462 1.00 0.330 None 1.000 3 0 2015 2016
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
P35670 ATPase copper transporting beta Transporter 182 0.529 0.654 4.8E-30 0.330 None 1.000 3 2 2002 2015