Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.500 6 0 2002 2016
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 hydrolase; protease 388 0.415 0.793 6.2E-18 0.500 2 0 2013 2015
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366
Q8N895 zinc finger protein 366 transcription factor 17 0.799 0.310 7.2E-02 0.500 2 0 2010 2011
Entrez Id: 1435
Gene Symbol: CSF1
CSF1
P09603 colony stimulating factor 1 153 0.510 0.655 0.99 0.310 1.000 2 0 1991 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.300 40 0 2000 2015
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.300 14 0 2008 2016
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.300 12 0 1995 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.300 8 0 2009 2015
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 393 0.421 0.828 0.33 0.300 8 0 1993 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.300 6 0 2006 2013
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.300 6 0 2003 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.300 5 0 2006 2009
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 322 0.432 0.793 0.78 0.300 4 0 2011 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.300 4 0 2008 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.300 4 0 2006 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.300 4 0 2008 2011
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 oxidoreductase 221 0.482 0.690 8.6E-06 0.300 4 0 2002 2017
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
P11388 DNA topoisomerase II alpha 122 0.542 0.621 1.00 0.300 4 0 2002 2012
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 195 0.494 0.621 1.2E-23 0.300 4 0 2002 2009
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 enzyme modulator; membrane traffic protein; structural protein; transmembrane receptor regulatory/adaptor protein 421 0.416 0.828 7.2E-03 0.300 4 0 2009 2011
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.300 4 0 2007 2013
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B hydrolase; nucleic acid binding 63 0.611 0.552 3.6E-15 0.300 4 0 2013 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.300 4 0 2002 2009
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.300 3 0 2003 2014
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.300 3 0 2004 2008