Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.300 None 1.000 3 0 2008 2009
Entrez Id: 114826
Gene Symbol: SMYD4
SMYD4
Q8IYR2 SET and MYND domain containing 4 11 0.792 0.077 8.8E-15 0.300 None 1.000 1 0 2009 2009
Entrez Id: 23081
Gene Symbol: KDM4C
KDM4C
Q9H3R0 lysine demethylase 4C 71 0.601 0.615 6.5E-07 0.300 None 1.000 1 0 2009 2009
Entrez Id: 23532
Gene Symbol: PRAME
PRAME
P78395 preferentially expressed antigen in melanoma 134 0.531 0.577 2.4E-07 0.300 None 1.000 1 0 2005 2005
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 1 0 1995 1995
Entrez Id: 6502
Gene Symbol: SKP2
SKP2
Q13309 S-phase kinase associated protein 2 204 0.492 0.808 0.96 0.300 None 1.000 1 0 2009 2009
Entrez Id: 7409
Gene Symbol: VAV1
VAV1
P15498 vav guanine nucleotide exchange factor 1 103 0.556 0.769 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.300 None 0 0
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 0.300 None 0 0
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2
Q9Y6C5 patched 2 114 0.563 0.692 3.4E-16 0.300 None 0 0
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 Calcium-binding protein 308 0.448 0.769 6.2E-03 0.300 None 1.000 1 0 2007 2007
Entrez Id: 6277
Gene Symbol: S100A6
S100A6
P06703 S100 calcium binding protein A6 Calcium-binding protein 168 0.510 0.808 0.18 0.300 None 1.000 1 0 2007 2007
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
P60903 S100 calcium binding protein A10 Calcium-binding protein 150 0.528 0.769 0.17 0.300 None 1.000 1 0 2007 2007
Entrez Id: 474
Gene Symbol: ATOH1
ATOH1
Q92858 atonal bHLH transcription factor 1 Enzyme 53 0.633 0.500 1.8E-02 0.300 None 1.000 1 0 2008 2008
Entrez Id: 7994
Gene Symbol: KAT6A
KAT6A
Q92794 lysine acetyltransferase 6A Enzyme 129 0.560 0.769 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.300 None 1.000 1 0 2011 2011
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
P24864 cyclin E1 Enzyme modulator 133 0.538 0.731 0.97 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
P26358 DNA methyltransferase 1 Epigenetic regulator 496 0.406 0.885 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 23030
Gene Symbol: KDM4B
KDM4B
O94953 lysine demethylase 4B Epigenetic regulator 71 0.606 0.462 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
O60885 bromodomain containing 4 Epigenetic regulator 335 0.446 0.885 1.00 0.300 None 1.000 1 0 2013 2013
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
P25440 bromodomain containing 2 Epigenetic regulator 303 0.450 0.808 1.00 0.300 None 1.000 1 0 2013 2013
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1
Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 371 0.460 0.808 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 8019
Gene Symbol: BRD3
BRD3
Q15059 bromodomain containing 3 Epigenetic regulator 42 0.700 0.500 0.97 0.300 None 1.000 1 0 2013 2013
Entrez Id: 84456
Gene Symbol: L3MBTL3
L3MBTL3
Q96JM7 L3MBTL histone methyl-lysine binding protein 3 Epigenetic regulator 35 0.700 0.423 1.00 0.300 None 1.000 1 0 2009 2009