Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.300 None 0.979 516 12 2005 2020
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.100 None 0.975 159 0 1993 2020
Entrez Id: 811
Gene Symbol: CALR
CALR 		P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.100 None 0.980 102 0 2014 2020
Entrez Id: 4352
Gene Symbol: MPL
MPL 		P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 222 0.510 0.692 4.1E-09 0.500 None 0.979 95 5 1995 2020
Entrez Id: 613
Gene Symbol: BCR
BCR 		P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.100 None 0.942 69 0 1992 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.100 None 1.000 34 0 1998 2018
Entrez Id: 6646
Gene Symbol: SOAT1
SOAT1 		P35610 sterol O-acyltransferase 1 Enzyme 389 0.424 0.846 7.4E-10 0.100 None 1.000 33 0 2006 2020
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB 		P09619 platelet derived growth factor receptor beta Kinase 492 0.416 0.846 0.90 0.300 None 1.000 24 0 2003 2019
Entrez Id: 54790
Gene Symbol: TET2
TET2 		Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.100 None 0.958 24 1 2009 2019
Entrez Id: 947
Gene Symbol: CD34
CD34 		P28906 CD34 molecule 674 0.368 0.808 5.0E-06 0.100 None 1.000 17 0 2008 2016
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.100 None 1.000 15 0 2003 2018
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A 		P42229 signal transducer and activator of transcription 5A Nucleic acid binding 318 0.445 0.808 1.00 0.100 None 1.000 13 0 2008 2018
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B 		P51692 signal transducer and activator of transcription 5B Nucleic acid binding 357 0.442 0.808 1.00 0.100 None 1.000 13 0 2008 2018
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1 		Q8IXJ9 ASXL transcriptional regulator 1 296 0.482 0.808 1.3E-14 0.300 None 1.000 13 0 2010 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.917 12 0 1993 2019
Entrez Id: 3716
Gene Symbol: JAK1
JAK1 		P23458 Janus kinase 1 Kinase 239 0.474 0.769 1.00 0.100 None 1.000 12 0 2009 2019
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		P36888 fms related receptor tyrosine kinase 3 Kinase 270 0.462 0.654 0.61 0.100 None 1.000 12 0 2002 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.100 None 0.909 11 3 2005 2018
Entrez Id: 867
Gene Symbol: CBL
CBL 		P22681 Cbl proto-oncogene Enzyme 172 0.527 0.769 6.1E-04 0.100 None 0.909 11 0 2009 2016
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.100 None 1.000 11 0 2001 2016
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.480 None 1.000 10 1 1994 2015
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.080 None 1.000 8 0 2012 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3 		Q9UQQ2 SH2B adaptor protein 3 212 0.527 0.692 1.0E-04 0.080 None 1.000 8 0 2010 2017