Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4352
Gene Symbol: MPL
MPL
P40238 MPL proto-oncogene, thrombopoietin receptor receptor 145 0.554 0.655 3.3E-09 0.500 0.976 46 5 2003 2017
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene receptor tyrosine kinase 462 0.394 0.759 0.99 0.480 1.000 10 2 1994 2016
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
P52333 Janus kinase 3 123 0.532 0.621 3.3E-05 0.400 4 1 2010 2015
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
P09619 platelet derived growth factor receptor beta 340 0.457 0.655 0.75 0.300 1.000 19 0 2003 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 373 0.430 0.690 0.47 0.100 0.939 280 4 2005 2018
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase 233 0.475 0.690 1.00 0.100 0.953 86 1 1993 2018
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR, RhoGEF and GTPase activating protein enzyme modulator 244 0.470 0.759 1.00 0.100 1.000 32 0 1990 2018
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin calcium-binding protein 196 0.492 0.793 0.90 0.100 0.929 28 0 2014 2018
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 623 0.388 0.759 1.00 0.100 1.000 23 0 1998 2017
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 191 0.499 0.586 1.7E-40 0.100 0.895 19 1 2003 2017
Entrez Id: 6646
Gene Symbol: SOAT1
SOAT1
P35610 sterol O-acyltransferase 1 transferase 185 0.484 0.793 1.4E-08 0.100 1.000 17 0 2007 2017
Entrez Id: 947
Gene Symbol: CD34
CD34
P28906 CD34 molecule 360 0.414 0.793 5.4E-06 0.100 1.000 13 0 2008 2016
Entrez Id: 867
Gene Symbol: CBL
CBL
P22681 Cbl proto-oncogene ligase 143 0.550 0.586 4.5E-03 0.090 0.889 9 0 2009 2016
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 runt related transcription factor 1 nucleic acid binding; transcription factor 248 0.467 0.690 0.88 0.090 0.889 9 0 2004 2016
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha 278 0.456 0.690 1.00 0.080 1.000 8 0 2003 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.080 0.875 8 0 1993 2016
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A nucleic acid binding; transcription factor 184 0.489 0.759 1.00 0.080 1.000 8 0 2007 2015
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B
P51692 signal transducer and activator of transcription 5B nucleic acid binding; transcription factor 178 0.490 0.690 1.00 0.080 1.000 8 0 2007 2015
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related tyrosine kinase 3 168 0.503 0.517 0.61 0.080 1.000 8 0 2002 2015
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma kinase; transferase 490 0.385 0.862 1.5E-06 0.060 1.000 6 0 2012 2016
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta kinase; transferase 468 0.389 0.862 1.00 0.060 1.000 6 0 2012 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.060 1.000 6 0 2012 2016
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
O14543 suppressor of cytokine signaling 3 enzyme modulator 187 0.487 0.724 0.75 0.060 1.000 6 1 2008 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta kinase; transferase 487 0.386 0.862 1.00 0.060 1.000 6 0 2012 2016
Entrez Id: 7066
Gene Symbol: THPO
THPO
P40225 thrombopoietin 125 0.542 0.552 0.22 0.050 1.000 5 0 1997 2012