Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
P15428 15-hydroxyprostaglandin dehydrogenase 194 0.516 0.731 1.4E-05 0.020 None 1.000 2 0 2012 2018
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.060 None 0.833 6 1 1998 2019
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.020 None 1.000 2 2 2007 2019
Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 104 0.561 0.808 0.25 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.030 None 1.000 3 3 2005 2013
Entrez Id: 430
Gene Symbol: ASCL2
ASCL2
Q99929 achaete-scute family bHLH transcription factor 2 Transcription factor 38 0.691 0.423 0.35 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 84519
Gene Symbol: ACRBP
ACRBP
Q8NEB7 acrosin binding protein 26 0.705 0.308 2.7E-10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.010 None 1.000 1 0 1997 1997
Entrez Id: 60312
Gene Symbol: AFAP1
AFAP1
Q8N556 actin filament associated protein 1 44 0.653 0.538 2.4E-07 0.010 None 1.000 1 0 2006 2006
Entrez Id: 214
Gene Symbol: ALCAM
ALCAM
Q13740 activated leukocyte cell adhesion molecule Cell adhesion 181 0.502 0.808 0.73 0.010 None 1.000 1 0 2018 2018
Entrez Id: 466
Gene Symbol: ATF1
ATF1
P18846 activating transcription factor 1 88 0.588 0.577 0.63 0.100 None 1.000 1 1 2019 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.010 None 1.000 1 0 2005 2005
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2016 2016
Entrez Id: 208
Gene Symbol: AKT2
AKT2
P31751 AKT serine/threonine kinase 2 Kinase 264 0.474 0.769 0.64 0.010 None 1.000 1 0 2014 2014
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.010 None 1.000 1 1 2011 2011
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 146 0.547 0.731 0.020 None 1.000 2 0 2003 2003
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 270 0.460 0.846 0.95 0.010 None 1.000 1 0 2017 2017
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.020 None 1.000 2 2 2005 2011
Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
P14550 aldo-keto reductase family 1 member A1 Enzyme 185 0.510 0.846 6.7E-07 0.020 None 1.000 2 0 2003 2003
Entrez Id: 23600
Gene Symbol: AMACR
AMACR
Q9UHK6 alpha-methylacyl-CoA racemase 179 0.510 0.769 2.7E-02 0.010 None 1.000 1 2 2007 2007
Entrez Id: 60529
Gene Symbol: ALX4
ALX4
Q9H161 ALX homeobox 4 129 0.560 0.692 0.36 0.010 None 1.000 1 0 2006 2006
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.200 None 1.000 59 6 1994 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.020 None 1.000 2 0 2001 2006
Entrez Id: 328
Gene Symbol: APEX1
APEX1
P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 305 0.458 0.846 1.9E-07 0.010 None 1.000 1 0 2013 2013