Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.100 0.975 673 8 1988 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.960 374 24 1989 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase 274 0.448 0.724 3.5E-06 0.100 0.984 123 0 2008 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.100 0.905 116 1 1993 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.100 0.950 100 3 1993 2018
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 oxidoreductase 262 0.458 0.828 1.2E-17 0.100 0.949 99 3 1984 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.100 0.929 70 2 1994 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.100 0.968 62 1 1989 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.100 0.982 55 1 2000 2018
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 264 0.449 0.828 4.8E-09 0.100 0.982 55 5 2001 2017
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 356 0.419 0.862 1.3E-04 0.100 0.920 50 0 1997 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.100 0.960 50 3 1995 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.100 1.000 50 2 1998 2016
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.100 0.977 43 0 1987 2015
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad 277 0.450 0.828 2.9E-02 0.100 1.000 43 0 1996 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.100 1.000 41 0 2007 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.100 0.976 41 7 2002 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 1.000 40 0 1996 2017
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit receptor; transporter 81 0.598 0.414 1.8E-06 0.100 0.950 40 6 2008 2016
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit receptor; transporter 84 0.584 0.448 1.2E-07 0.100 1.000 39 13 2008 2017
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit nucleic acid binding 362 0.447 0.828 1.7E-20 0.100 0.897 39 2 2001 2014
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS
O60760 hematopoietic prostaglandin D synthase 349 0.415 0.828 1.7E-06 0.100 1.000 37 0 1991 2015
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.100 0.944 36 1 2007 2017
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
O15527 8-oxoguanine DNA glycosylase 218 0.476 0.759 2.1E-12 0.100 0.944 36 3 1998 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.100 0.971 34 1 2002 2018