Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.300 28 0 1997 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.300 6 0 2006 2016
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.300 5 0 2002 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.300 3 0 1993 2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.300 3 0 2003 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.300 2 0 2003 2011
Entrez Id: 1593
Gene Symbol: CYP27A1
CYP27A1
Q02318 cytochrome P450 family 27 subfamily A member 1 oxidoreductase 122 0.582 0.655 2.4E-19 0.300 2 0 2001 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.300 2 0 2003 2011
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen enzyme modulator 451 0.406 0.862 3.9E-08 0.300 2 0 2012 2012
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 232 0.472 0.724 3.4E-16 0.300 2 0 2010 2010
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
P19320 vascular cell adhesion molecule 1 232 0.466 0.793 0.74 0.300 1 0 2003 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.300 1 0 2011 2011
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.300 1 0 2009 2009
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type hydrolase; protease 267 0.459 0.828 3.5E-05 0.300 1 0 2003 2003
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
P14555 phospholipase A2 group IIA hydrolase 148 0.509 0.690 0.11 0.300 1 0 2009 2009
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.300 1 0 2010 2010
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 enzyme modulator 506 0.384 0.793 4.7E-02 0.300 1 0 2003 2003
Entrez Id: 4864
Gene Symbol: NPC1
NPC1
O15118 NPC intracellular cholesterol transporter 1 173 0.536 0.690 2.8E-05 0.300 1 0 2008 2008
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 201 0.485 0.724 5.0E-09 0.300 1 0 2009 2009
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
P10147 C-C motif chemokine ligand 3 signaling molecule 133 0.522 0.828 0.36 0.300 1 0 2014 2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.300 1 0 2006 2006
Entrez Id: 7274
Gene Symbol: TTPA
TTPA
P49638 alpha tocopherol transfer protein transfer/carrier protein 112 0.642 0.379 1.5E-03 0.300 1 0 2001 2001
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.300 1 0 2011 2011
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.300 1 0 2002 2002
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.300 1 0 2010 2010