Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4, p53 regulator nucleic acid binding 159 0.501 0.724 1.00 0.540 1.000 4 0 2002 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 237 0.469 0.655 0.87 0.520 1.000 4 1 2009 2016
Entrez Id: 3020
Gene Symbol: H3F3A
H3F3A
P84243 H3 histone family member 3A nucleic acid binding 30 0.667 0.310 0.13 0.520 1.000 4 0 2012 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 0.958 123 2 1988 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.500 0.941 17 0 2005 2017
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
P25440 bromodomain containing 2 174 0.488 0.690 1.00 0.500 1 0 2016 2016
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
Q05397 protein tyrosine kinase 2 112 0.545 0.655 1.00 0.500 1 0 2003 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.450 0.800 6 1 1995 2016
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.420 1.000 4 2 2009 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.400 0.945 57 0 1999 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.955 23 0 1993 2015
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 membrane traffic protein 306 0.450 0.793 2.4E-18 0.400 1.000 21 0 2008 2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.400 0.842 19 2 2008 2016
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.400 1.000 16 0 1992 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.400 0.929 15 0 2003 2016
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.370 1.000 8 0 2012 2016
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
P36222 chitinase 3 like 1 167 0.502 0.793 8.5E-06 0.350 0.800 6 0 2002 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.350 1.000 6 0 2006 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.350 1.000 6 0 1996 2013
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha 278 0.456 0.690 1.00 0.350 1.000 5 0 1996 2016
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
P24941 cyclin dependent kinase 2 kinase; transferase 195 0.478 0.690 0.89 0.350 1.000 5 0 1995 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.340 1.000 5 0 2007 2014
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.340 1.000 5 0 2009 2014
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.340 1.000 4 0 2005 2015
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 signaling molecule 461 0.399 0.828 1.2E-03 0.330 1.000 4 0 2007 2016