Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 enzyme modulator 308 0.458 0.724 1.00 0.300 2 0 2010 2013
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.300 1 0 2011 2011
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.300 1 0 2011 2011
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
Q16620 neurotrophic receptor tyrosine kinase 2 165 0.514 0.586 1.00 0.300 1 0 2013 2013
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase, non-receptor type 11 441 0.429 0.828 1.00 0.300 1 0 2013 2013
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
Q9Y6Q9 nuclear receptor coactivator 3 transcription factor; transferase 96 0.548 0.448 0.55 0.300 1 0 2015 2015
Entrez Id: 9113
Gene Symbol: LATS1
LATS1
O95835 large tumor suppressor kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 54 0.602 0.379 1.00 0.300 1 0 2007 2007
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
Q92597 N-myc downstream regulated 1 hydrolase; protease 158 0.521 0.655 7.7E-03 0.300 1 0 2005 2005
Entrez Id: 10683
Gene Symbol: DLL3
DLL3
Q9NYJ7 delta like canonical Notch ligand 3 72 0.609 0.414 5.7E-05 0.300 1 0 2011 2011
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 transcription factor 70 0.579 0.552 5.1E-02 0.300 1 0 2011 2011
Entrez Id: 23493
Gene Symbol: HEY2
HEY2
Q9UBP5 hes related family bHLH transcription factor with YRPW motif 2 transcription factor 57 0.609 0.517 0.90 0.300 1 0 2011 2011
Entrez Id: 26524
Gene Symbol: LATS2
LATS2
Q9NRM7 large tumor suppressor kinase 2 calcium-binding protein; kinase; transfer/carrier protein; transferase 53 0.616 0.448 0.99 0.300 1 0 2007 2007
Entrez Id: 57670
Gene Symbol: KIAA1549
KIAA1549
Q9HCM3 KIAA1549 25 0.676 0.138 0.99 0.300 1 0 2013 2013
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 kinase; receptor; transferase 102 0.573 0.552 0.38 0.300 1 0 2014 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.300 1 0 2010 2010
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor nucleic acid binding; receptor; transcription factor 564 0.380 0.793 0.98 0.300 1 0 2015 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.300 1 0 2013 2013
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.300 1 0 2015 2015
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 nucleic acid binding; receptor; transcription factor 297 0.445 0.828 5.4E-08 0.300 1 0 2015 2015
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 623 0.388 0.759 1.00 0.300 1 0 2013 2013
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.300 1 0 2001 2001
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.300 1 0 2005 2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.300 1 0 2013 2013
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.300 1 0 2001 2001
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 hydrolase; protease 309 0.439 0.793 4.9E-15 0.300 1 0 2010 2010