Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.770 None 1.000 12 16 2009 2020
Entrez Id: 10000
Gene Symbol: AKT3
AKT3
Q9Y243 AKT serine/threonine kinase 3 Kinase 183 0.512 0.808 1.00 0.100 None 1.000 5 1 2012 2017
Entrez Id: 5296
Gene Symbol: PIK3R2
PIK3R2
O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 120 0.551 0.808 1.6E-02 0.100 None 1.000 4 1 2012 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.020 None 1.000 2 0 2017 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.020 None 1.000 2 0 2017 2020
Entrez Id: 4594
Gene Symbol: MMUT
MMUT
P22033 methylmalonyl-CoA mutase Enzyme 147 0.534 0.731 1.7E-22 0.020 None 1.000 2 0 2019 2019
Entrez Id: 55388
Gene Symbol: MCM10
MCM10
Q7L590 minichromosome maintenance 10 replication initiation factor 28 0.691 0.462 4.4E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5921
Gene Symbol: RASA1
RASA1
P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 8318
Gene Symbol: CDC45
CDC45
O75419 cell division cycle 45 Nucleic acid binding 102 0.588 0.692 4.6E-05 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2020 2020
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
O60885 bromodomain containing 4 Epigenetic regulator 335 0.446 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 508 0.398 0.885 4.3E-10 0.010 None 1.000 1 0 2012 2012
Entrez Id: 8831
Gene Symbol: SYNGAP1
SYNGAP1
Q96PV0 synaptic Ras GTPase activating protein 1 Enzyme modulator 145 0.584 0.577 1.00 0.010 None 1.000 1 0 2010 2010