Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 0.963 139 0 1988 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.968 126 0 1989 2018
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
microRNA 122 117 0.535 0.724 0.400 0.965 86 0 2007 2018
Entrez Id: 2719
Gene Symbol: GPC3
GPC3
P51654 glypican 3 239 0.502 0.724 1.00 0.400 0.976 85 0 1997 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.400 0.963 83 0 1991 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 0.986 80 0 1993 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.400 0.986 77 0 1992 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.986 74 0 1992 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.968 69 4 2000 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 0.969 68 0 1996 2017
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.400 0.983 67 3 1998 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.400 0.962 62 0 1991 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 0.946 59 0 2003 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 1.000 58 0 1999 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.400 1.000 56 1 1987 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.400 0.978 53 0 1985 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.400 0.939 51 0 1996 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.400 1.000 40 0 1995 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.400 1.000 36 0 1990 2016
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.400 0.882 35 0 1995 2015
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 334 0.424 0.724 0.66 0.400 1.000 34 1 1998 2015
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 oxidoreductase 262 0.458 0.828 1.2E-17 0.400 0.879 33 1 1983 2017
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 enzyme modulator 191 0.479 0.655 5.7E-02 0.400 0.952 32 0 2003 2015
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.400 0.933 32 2 1988 2017
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.400 0.964 31 0 2007 2017