Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.900 0.945 560 68 1990 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.800 0.965 91 11 2002 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.800 0.956 81 12 1998 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.800 0.973 41 3 1991 2018
Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1
O15169 axin 1 69 0.600 0.483 0.73 0.800 1.000 11 4 2000 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.700 1.000 19 1 1999 2017
Entrez Id: 3482
Gene Symbol: IGF2R
IGF2R
P11717 insulin like growth factor 2 receptor receptor 110 0.545 0.655 1.00 0.700 1.000 15 2 1995 2014
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.600 0.963 27 0 1990 2016
Entrez Id: 10553
Gene Symbol: HTATIP2
HTATIP2
Q9BUP3 HIV-1 Tat interactive protein 2 35 0.663 0.310 5.7E-13 0.600 1.000 12 1 2004 2016
Entrez Id: 196528
Gene Symbol: ARID2
ARID2
Q68CP9 AT-rich interaction domain 2 81 0.645 0.621 1.00 0.580 1.000 9 0 2011 2017
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
P21439 ATP binding cassette subfamily B member 4 hydrolase; protease 108 0.555 0.517 4.5E-07 0.570 0.857 8 1 1993 2016
Entrez Id: 57492
Gene Symbol: ARID1B
ARID1B
Q8NFD5 AT-rich interaction domain 1B 187 0.561 0.655 1.00 0.510 1.000 2 0 2012 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.500 0.949 102 3 1996 2017
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.500 0.927 59 0 1989 2018
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 enzyme modulator 284 0.453 0.793 4.2E-08 0.500 1.000 30 0 1981 2012
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.500 0.958 24 1 1992 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.500 0.941 18 3 2005 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.500 0.900 15 6 1987 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.500 0.900 11 2 1993 2016
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 nucleic acid binding; transcription factor 161 0.515 0.690 0.78 0.500 1.000 10 5 2013 2016
Entrez Id: 9681
Gene Symbol: DEPDC5
DEPDC5
O75140 DEP domain containing 5 nucleic acid binding 34 0.672 0.448 7.2E-02 0.460 1.000 7 2 2011 2016
Entrez Id: 5218
Gene Symbol: CDK14
CDK14
O94921 cyclin dependent kinase 14 kinase; transferase 17 0.713 0.241 1.7E-08 0.440 1.000 5 1 2007 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.430 0.667 5 2 2012 2016
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN
Q9H040 SprT-like N-terminal domain 42 0.762 0.345 0.97 0.420 1.000 2 0 2015 2017
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein transfer/carrier protein 181 0.502 0.724 1.2E-11 0.400 0.958 469 0 1980 2018