Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 232 0.477 0.724 1.6E-16 0.500 1.000 19 0 1996 2015
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.420 1.000 3 2 2011 2016
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
P35670 ATPase copper transporting beta hydrolase; transporter 166 0.547 0.621 5.4E-30 0.410 1.000 2 0 2007 2016
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
Q9NST1 patatin like phospholipase domain containing 3 hydrolase; transferase 85 0.584 0.552 4.0E-07 0.400 0.920 87 3 2009 2018
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase transferase 155 0.510 0.828 7.1E-19 0.400 0.893 29 0 2001 2016
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha nucleic acid binding; receptor; transcription factor 247 0.465 0.793 3.7E-02 0.400 0.960 26 0 2005 2018
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 90 0.570 0.517 1.9E-02 0.400 0.958 25 0 2007 2017
Entrez Id: 4547
Gene Symbol: MTTP
MTTP
P55157 microsomal triglyceride transfer protein transfer/carrier protein; transporter 144 0.526 0.690 1.4E-05 0.400 0.913 24 0 2001 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.955 23 0 1997 2016
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.400 1.000 16 0 2010 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.400 0.909 16 0 2001 2017
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 212 0.473 0.759 3.9E-07 0.400 0.909 12 0 2003 2015
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 oxidoreductase 221 0.482 0.690 8.6E-06 0.400 1 0 2002 2002
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 signaling molecule 60 0.614 0.483 3.0E-02 0.370 1.000 8 0 2010 2016
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 220 0.470 0.759 0.350 1.000 6 0 2012 2016
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
Q03181 peroxisome proliferator activated receptor delta nucleic acid binding; receptor; transcription factor 122 0.551 0.621 0.99 0.350 1.000 6 0 2008 2016
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 nucleic acid binding; receptor; transcription factor 149 0.522 0.655 1.3E-03 0.350 1.000 6 0 2013 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.340 1.000 6 0 2008 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.340 1.000 5 0 2012 2017
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
Q13133 nuclear receptor subfamily 1 group H member 3 nucleic acid binding; receptor; transcription factor 48 0.621 0.517 0.91 0.340 1.000 5 0 2011 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.340 1.000 5 0 2011 2016
Entrez Id: 4143
Gene Symbol: MAT1A
MAT1A
Q00266 methionine adenosyltransferase 1A transferase 65 0.614 0.517 3.8E-03 0.330 1.000 4 0 2002 2010
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor defense/immunity protein; signaling molecule 264 0.474 0.793 1.00 0.330 1.000 4 1 2007 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.330 0.667 4 0 2000 2008
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 nucleic acid binding; receptor; transcription factor 263 0.455 0.793 6.2E-09 0.330 1.000 3 1 2013 2016