Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.100 1.000 12 0 1995 2016
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 167 0.500 0.724 3.9E-03 0.080 1.000 8 0 1987 2014
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.040 1.000 4 1 1999 2008
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 calcium-binding protein; hydrolase; protease; signaling molecule 268 0.490 0.690 0.98 0.040 1.000 4 1 1997 2008
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin transfer/carrier protein; transporter 258 0.471 0.897 0.55 0.020 1.000 2 0 2005 2005
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase hydrolase; protease 237 0.461 0.690 7.0E-17 0.020 1.000 2 0 2007 2010
Entrez Id: 9445
Gene Symbol: ITM2B
ITM2B
Q9Y287 integral membrane protein 2B 58 0.667 0.448 0.65 0.010 1.000 1 0 2014 2014
Entrez Id: 6855
Gene Symbol: SYP
SYP
P08247 synaptophysin membrane traffic protein 101 0.550 0.690 0.90 0.010 1.000 1 0 1995 1995
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
P49810 presenilin 2 hydrolase; protease; signaling molecule 108 0.567 0.517 2.4E-03 0.010 1.000 1 1 1998 1998
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 enzyme modulator; extracellular matrix protein; receptor 400 0.419 0.931 3.6E-12 0.010 1.000 1 0 2006 2006
Entrez Id: 3416
Gene Symbol: IDE
IDE
P14735 insulin degrading enzyme hydrolase; protease 47 0.627 0.483 9.1E-03 0.010 1.000 1 0 2010 2010
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
P14136 glial fibrillary acidic protein 220 0.484 0.759 1.2E-06 0.010 1.000 1 0 1995 1995
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.010 1.000 1 0 2011 2011
Entrez Id: 1509
Gene Symbol: CTSD
CTSD
P07339 cathepsin D hydrolase; protease 175 0.505 0.759 1.1E-03 0.010 1.000 1 0 1995 1995
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 signaling molecule 670 0.356 0.966 0.84 0.010 1.000 1 0 2006 2006
Entrez Id: 780
Gene Symbol: DDR1
DDR1
Q08345 discoidin domain receptor tyrosine kinase 1 118 0.533 0.690 5.2E-06 0.010 1.000 1 0 2007 2007
Entrez Id: 445
Gene Symbol: ASS1
ASS1
P00966 argininosuccinate synthase 1 ligase 114 0.558 0.759 1.8E-09 0.010 1.000 1 0 2001 2001
Entrez Id: 10194
Gene Symbol: TSHZ1
TSHZ1
Q6ZSZ6 teashirt zinc finger homeobox 1 transcription factor 51 0.621 0.552 1.00 0.010 1.000 1 0 2002 2002