Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.700 None 0.924 92 13 1992 2019
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CDKN2B antisense RNA 1 213 0.491 0.769 0.430 None 1.000 5 3 2010 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.400 None 1.000 49 0 2002 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 None 1.000 29 0 1995 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.400 None 1.000 28 1 2009 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.400 None 0.958 24 0 2000 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.400 None 0.864 22 5 2003 2020
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.400 None 1.000 15 0 2009 2019
Entrez Id: 1182
Gene Symbol: CLCN3
CLCN3
P51790 chloride voltage-gated channel 3 Ion channel 67 0.621 0.615 1.00 0.400 None 1.000 10 0 2008 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.340 None 1.000 5 0 2000 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.340 None 0.800 5 1 2009 2015
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.320 None 1.000 3 0 2010 2010
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.320 None 0.667 3 0 2012 2019
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA
P25963 NFKB inhibitor alpha 226 0.487 0.885 0.99 0.320 None 1.000 2 2 2013 2016
Entrez Id: 208
Gene Symbol: AKT2
AKT2
P31751 AKT serine/threonine kinase 2 Kinase 264 0.474 0.769 0.64 0.310 None 1.000 2 0 2014 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.310 None 1.000 2 0 2003 2014
Entrez Id: 1475
Gene Symbol: CSTA
CSTA
P01040 cystatin A Enzyme modulator 97 0.592 0.731 1.5E-04 0.310 None 1.000 1 0 2010 2010
Entrez Id: 442911
Gene Symbol: MIR346
MIR346
microRNA 346 52 0.631 0.615 0.310 None 1.000 1 0 2016 2016
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
Q04912 macrophage stimulating 1 receptor Kinase 133 0.542 0.808 7.9E-37 0.310 None 1.000 1 1 2016 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.300 None 1.000 1 0 2014 2014
Entrez Id: 23345
Gene Symbol: SYNE1
SYNE1
Q8NF91 spectrin repeat containing nuclear envelope protein 1 237 0.511 0.846 3.2E-52 0.300 None 1.000 1 0 2014 2014
Entrez Id: 170712
Gene Symbol: COX7B2
COX7B2
Q8TF08 cytochrome c oxidase subunit 7B2 2 0.931 0.154 0.300 limited 0 0
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
P04439 major histocompatibility complex, class I, A 672 0.370 0.846 1.3E-03 0.200 None 0.944 18 10 1983 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.190 None 1.000 10 1 2003 2017
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.180 None 1.000 9 1 2002 2018