Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.500 0.945 75 3 1992 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 1.000 22 0 1995 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 1.000 19 0 2002 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 1.000 18 0 2000 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 1.000 15 1 2010 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.400 0.857 14 2 2003 2016
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit nucleic acid binding 276 0.463 0.724 2.1E-07 0.370 1.000 8 0 2009 2018
Entrez Id: 1182
Gene Symbol: CLCN3
CLCN3
P51790 chloride voltage-gated channel 3 transporter 35 0.667 0.483 1.00 0.370 1.000 7 0 2008 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.330 0.667 4 0 2012 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.320 1.000 3 0 2000 2015
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CDKN2B antisense RNA 1 99 0.550 0.586 0.310 1.000 2 3 2017 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.310 1.000 2 0 2010 2010
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA
P25963 NFKB inhibitor alpha 151 0.509 0.724 0.99 0.310 1.000 1 0 2013 2013
Entrez Id: 1475
Gene Symbol: CSTA
CSTA
P01040 cystatin A enzyme modulator 53 0.633 0.483 1.4E-04 0.310 1.000 1 0 2010 2010
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
Q04912 macrophage stimulating 1 receptor 83 0.582 0.483 3.2E-36 0.310 1.000 1 1 2016 2016
Entrez Id: 442911
Gene Symbol: MIR346
MIR346
microRNA 346 22 0.713 0.414 0.300 1 0 2017 2017
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 211 0.505 0.724 1.00 0.300 1 0 2015 2015
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 222 0.473 0.690 6.7E-15 0.300 1 0 2015 2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.300 1 0 2015 2015
Entrez Id: 208
Gene Symbol: AKT2
AKT2
P31751 AKT serine/threonine kinase 2 calcium-binding protein; kinase; transfer/carrier protein; transferase 163 0.512 0.655 0.61 0.300 1 0 2015 2015
Entrez Id: 23345
Gene Symbol: SYNE1
SYNE1
Q8NF91 spectrin repeat containing nuclear envelope protein 1 95 0.594 0.621 9.1E-50 0.300 1 0 2015 2015
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
Q9NR12 PDZ and LIM domain 7 cytoskeletal protein 139 0.521 0.690 0.69 0.100 0.986 138 0 1991 2017
Entrez Id: 4864
Gene Symbol: NPC1
NPC1
O15118 NPC intracellular cholesterol transporter 1 173 0.536 0.690 2.8E-05 0.100 0.918 49 2 1998 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.100 1.000 18 1 2009 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 0.882 17 0 1993 2014