Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2017 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.020 None 1.000 2 0 2014 2018
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
P11387 DNA topoisomerase I Enzyme 143 0.542 0.692 1.00 0.020 None 1.000 2 0 2013 2013
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.020 None 1.000 2 1 2008 2013
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.020 None 1.000 2 0 2013 2013
Entrez Id: 8511
Gene Symbol: MMP23A
MMP23A
matrix metallopeptidase 23A (pseudogene) 27 0.722 0.308 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
P11465 pregnancy specific beta-1-glycoprotein 2 210 0.492 0.731 1.4E-30 0.010 None 1.000 1 0 2017 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2017 2017
Entrez Id: 641455
Gene Symbol: POTEM
POTEM
A6NI47 POTE ankyrin domain family member M 133 0.541 0.769 3.2E-04 0.010 None 1.000 1 0 2013 2013
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 synthesis of cytochrome C oxidase 2 Enzyme 294 0.479 0.846 7.5E-07 0.010 None 1.000 1 0 2013 2013
Entrez Id: 695
Gene Symbol: BTK
BTK
Q06187 Bruton tyrosine kinase Kinase 290 0.464 0.808 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 71
Gene Symbol: ACTG1
ACTG1
P63261 actin gamma 1 Cellular structure 291 0.477 0.846 4.8E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 9457
Gene Symbol: FHL5
FHL5
Q5TD97 four and a half LIM domains 5 Transcription factor 153 0.530 0.769 4.8E-10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2020 2020
Entrez Id: 72
Gene Symbol: ACTG2
ACTG2
P63267 actin gamma 2, smooth muscle Cellular structure 205 0.505 0.808 7.1E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8761
Gene Symbol: PABPC4
PABPC4
Q13310 poly(A) binding protein cytoplasmic 4 26 0.729 0.346 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.010 None 1.000 1 0 2013 2013
Entrez Id: 79623
Gene Symbol: GALNT14
GALNT14
Q96FL9 polypeptide N-acetylgalactosaminyltransferase 14 Enzyme 48 0.631 0.538 7.1E-17 0.010 None 1.000 1 0 2016 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8510
Gene Symbol: MMP23B
MMP23B
O75900 matrix metallopeptidase 23B Enzyme 32 0.695 0.346 0.12 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4659
Gene Symbol: PPP1R12A
PPP1R12A
O14974 protein phosphatase 1 regulatory subunit 12A 59 0.626 0.615 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.010 None 1.000 1 1 2011 2011