Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 0.986 145 1 2006 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 0.962 26 0 2006 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.100 None 0.929 14 0 2008 2020
Entrez Id: 80139
Gene Symbol: ZNF703
ZNF703
Q9H7S9 zinc finger protein 703 21 0.722 0.269 0.36 0.040 None 1.000 4 0 2011 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 1.000 4 0 2017 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.040 None 1.000 4 0 2014 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.040 None 1.000 4 0 2012 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.030 None 1.000 3 0 2012 2017
Entrez Id: 5768
Gene Symbol: QSOX1
QSOX1
O00391 quiescin sulfhydryl oxidase 1 Enzyme 43 0.670 0.577 2.6E-05 0.030 None 1.000 3 0 2013 2018
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.030 None 1.000 3 0 2016 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.020 None 1.000 2 1 2014 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.020 None 0.500 2 0 2017 2019
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.020 None 1.000 2 0 2011 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5162
Gene Symbol: PDHB
PDHB
P11177 pyruvate dehydrogenase E1 subunit beta 21 0.711 0.385 0.15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9833
Gene Symbol: MELK
MELK
Q14680 maternal embryonic leucine zipper kinase Kinase 94 0.566 0.577 4.5E-22 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 54458
Gene Symbol: PRR13
PRR13
Q9NZ81 proline rich 13 11 0.769 0.308 1.4E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 54863
Gene Symbol: TOR4A
TOR4A
Q9NXH8 torsin family 4 member A Chaperone 3 0.890 0.077 0.56 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.010 None 1.000 1 0 2019 2019
Entrez Id: 56477
Gene Symbol: CCL28
CCL28
Q9NRJ3 C-C motif chemokine ligand 28 85 0.587 0.769 5.2E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
Q96GD0 pyridoxal phosphatase Enzyme 149 0.533 0.731 0.26 0.010 None 1.000 1 0 2012 2012
Entrez Id: 51014
Gene Symbol: TMED7
TMED7
Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 336 0.436 0.808 0.48 0.010 None 1.000 1 0 2018 2018
Entrez Id: 51008
Gene Symbol: ASCC1
ASCC1
Q8N9N2 activating signal cointegrator 1 complex subunit 1 209 0.495 0.846 2.6E-14 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.010 None < 0.001 1 1 2019 2019