Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.100 None 0.983 177 2 2006 2020
Entrez Id: 2896
Gene Symbol: GRN
GRN
P28799 granulin precursor 412 0.435 0.846 7.0E-02 0.100 None 0.990 100 3 2006 2020
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72
Q96LT7 C9orf72-SMCR8 complex subunit 258 0.496 0.769 1.1E-06 0.100 None 0.981 54 0 2012 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS
P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.100 None 1.000 30 1 2010 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.100 None 1.000 26 2 2003 2019
Entrez Id: 54664
Gene Symbol: TMEM106B
TMEM106B
Q9NUM4 transmembrane protein 106B 126 0.590 0.462 0.33 0.100 None 1.000 17 0 2011 2018
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.080 None 1.000 8 0 2012 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.070 None 1.000 7 0 2001 2013
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B
Q9UQN3 charged multivesicular body protein 2B 177 0.543 0.731 4.6E-06 0.060 None 1.000 6 0 2006 2012
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 289 0.457 0.846 0.99 0.050 None 1.000 5 0 2012 2017
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.050 None 1.000 5 2 2007 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.050 None 1.000 5 1 2007 2019
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Q9UJW0 dynactin subunit 4 253 0.472 0.846 0.73 0.040 None 1.000 4 0 2012 2017
Entrez Id: 23636
Gene Symbol: NUP62
NUP62
P37198 nucleoporin 62 Transporter 273 0.470 0.885 0.95 0.040 None 1.000 4 0 2012 2017
Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1
P32780 general transcription factor IIH subunit 1 Transcription factor 258 0.469 0.846 0.99 0.040 None 1.000 4 0 2012 2017
Entrez Id: 29978
Gene Symbol: UBQLN2
UBQLN2
Q9UHD9 ubiquilin 2 59 0.656 0.462 0.85 0.040 None 1.000 4 0 2013 2016
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.030 None 1.000 3 1 2007 2009
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
Q99700 ataxin 2 Nucleic acid binding 341 0.482 0.808 0.85 0.030 None 1.000 3 0 2012 2017
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.030 None 1.000 3 0 2019 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.030 None 0.667 3 0 2009 2019
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS
P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.030 None 1.000 3 0 2007 2019
Entrez Id: 8148
Gene Symbol: TAF15
TAF15
Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 74 0.626 0.500 0.17 0.030 None 1.000 3 0 2012 2017
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.030 None 1.000 3 0 2019 2020
Entrez Id: 9939
Gene Symbol: RBM8A
RBM8A
Q9Y5S9 RNA binding motif protein 8A 99 0.604 0.692 0.57 0.020 None 0.500 2 0 2017 2018
Entrez Id: 3178
Gene Symbol: HNRNPA1
HNRNPA1
P09651 heterogeneous nuclear ribonucleoprotein A1 188 0.529 0.885 1.00 0.020 None 1.000 2 0 2011 2012