Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease BEFREE This meta-analysis showed that T allele of rs2227564 polymorphism in PLAU gene could increase the effects on risk of AD, and this result needs to be confirmed by further studies. 23813610 2013
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease BEFREE We have evaluated variants in seven Aβ-degrading genes (ACE, ECE1, ECE2, IDE, MME, PLAU, and TF) for association with AD risk in the Genetic and Environmental Risk in Alzheimer's Disease Consortium 1 (GERAD1) cohort, and with three cognitive phenotypes in the Lothian Birth Cohort 1936 (LBC1936), using 128 and 121 SNPs, respectively. 22693153 2012
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease LHGDN Our data support a role for PLAU_1 as an independent genetic risk factor for AD in the Italian population for those subjects who do not have the APOE-epsilon4 allele. 17174555 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease BEFREE Our data support a role for PLAU_1 as an independent genetic risk factor for AD in the Italian population for those subjects who do not have the APOE-epsilon4 allele. 17174555 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease LHGDN In this study we evaluated the distribution of four tagSNPs (rs2227562 in intron 5, rs2227564 in exon 6, rs2227571 in intron 9, and rs4065 in 3'UTR) in the PLAU gene in a large case-control study consisting of up to 1,000 AD patients and 697 white control subjects. 16967469 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease BEFREE Previously some studies have examined the role of common variation in the PLAU gene with AD risk but the results have been inconsistent and this inconsistency could have been due to the use of relatively small sample sizes. 16967469 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease BEFREE A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease. 16825285 2006
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease LHGDN A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease. 16825285 2006
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease BEFREE No association of a non-synonymous PLAU polymorphism with Alzheimer's disease and disease-related traits. 15558716 2005
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 GeneticVariation disease LHGDN Association of late-onset Alzheimer disease with a genotype of PLAU, the gene encoding urokinase-type plasminogen activator on chromosome 10q22.2. 12898287 2003
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease BEFREE We interpret these observations as suggesting that uPA represents a possible candidate gene for the chromosome 10 familial AD locus. 12271474 2002
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease MGD
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease CTD_human
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.680 Biomarker disease HPO