|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
|
30929738 |
2019 |
|
HLA-DQA1
|
0.490 |
Biomarker
|
disease |
BEFREE |
By linking DEGs to the genome-wide association study (GWAS) catalog and the lung and blood eQTL annotation data from GTEx, we identified four male-specific genes (FBXL7, ITPR3 and RAD51B from epithelial tissue and ALOX15 from blood) and one female-specific gene (HLA-DQA1 from epithelial tissue) that are disregulated during asthma.
|
31095684 |
2019 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
|
31036433 |
2019 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
|
29273806 |
2018 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
|
29785011 |
2018 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Identification of a new locus at 16q12 associated with time to asthma onset.
|
27130862 |
2016 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
Detection and interpretation of shared genetic influences on 42 human traits.
|
27182965 |
2016 |
|
HLA-DQA1
|
0.490 |
AlteredExpression
|
disease |
BEFREE |
The cluster analysis of these DEGs showed that 4 genes, including human leukocyte antigen (HLA-DQA1), HLA-DRB4, integrin 3 (ITGB3) and killer cell lectin-like receptor subfamily F member 1 (KLRF1) were all significantly expressed in 3 groups, which were significantly enriched in asthma, T1D and intestinal immune network for IgA production pathway.
|
24838153 |
2014 |
|
HLA-DQA1
|
0.490 |
Biomarker
|
disease |
BEFREE |
HLA-DQA1 is the fourth member of the HLA family found to be associated with asthma, in addition to the previously identified HLA-DRA, HLA-DQB1 and HLA-DQA2.
|
23181788 |
2012 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASCAT |
HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.
|
23181788 |
2012 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASDB |
HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.
|
23181788 |
2012 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
GWASDB |
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
|
21150878 |
2011 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
These data suggests that HLA-DRB1, DQA1 & DQB1 alleles and haplotypes might be implicated in susceptibility to allergy and asthma and serum IgE production.
|
19052351 |
2008 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
This study was conducted to investigate whether susceptibility or resistance to asthma is associated with HLA-DQA1 and DQB1 genes polymorphism.
|
12890388 |
2003 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
LHGDN |
The alleles HLA-DQA1 * 0104 and HLA-DQB1 * 0201 are correlated with the susceptibility to asthma among Northern of Han nationality.
|
11953202 |
2002 |
|
HLA-DQA1
|
0.490 |
Biomarker
|
disease |
CTD_human |
The frequencies of DQA1*0104 and DQB1*0503 were significantly increased in asthmatics compared with asymptomatic exposed subjects, while DQA1*0101 and DQB1*0501 were significantly increased in asymptomatic exposed subjects.
|
10792356 |
2000 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
We have identified an association between the haplotype HLA-DRB1*1101, DQA1*0501, DQB1*0301 and atopic asthma that confers susceptibility to develop mite-sensitive asthma to atopics (relative risk, RR 8.2), and to non-atopic controls (RR = 15.8) that carry this haplotype.
|
10051703 |
1999 |
|
HLA-DQA1
|
0.490 |
Biomarker
|
disease |
BEFREE |
We investigated the human leukocyte antigen (HLA) genes DRB1,3,4,5, DQB1, and DQA1 in 55 isocyanate-exposed patients with workplace-related dyspnea (32 asthmatics, 23 nonasthmatics) and 90 nonexposed controls.
|
9327077 |
1997 |
|
HLA-DQA1
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
No significant difference was found in the distribution of DQA1 alleles between asthmatics and controls.
|
8777952 |
1996 |