Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.340 Biomarker disease BEFREE Transforming growth factor beta receptor family ligands inhibit hepatocyte growth factor synthesis and secretion from astrocytoma cells. 14969747 2004
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.340 AlteredExpression disease BEFREE Here we report that secretion and expression of HGF in U87 astrocytoma is increased by a PKC activator, PMA, an effect which is abolished by a PKC inhibitor, Go6976, specific for PKCalpha and PKCbeta1. 12191496 2002
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.340 Biomarker disease CTD_human Agonists of the retinoic acid- and retinoid X-receptors inhibit hepatocyte growth factor secretion and expression in U87 human astrocytoma cells. 11223164 2001
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.340 Biomarker disease BEFREE Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas. 11296484 2001
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.340 AlteredExpression disease BEFREE Taken together, our results show for the first time that retinoids, acting via the RAR and RxRs, significantly inhibit both the secretion and expression of HGF, thereby interrupting a potentially highly tumorigenic autocrine loop in astrocytoma cells. 11223164 2001