| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | group | BEFREE | Interleukin-17 (IL-17) is a potent proinflammatory cytokine that protects a host against fungal and extracellular bacterial infections. | 30765202 | 2019 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Overall, the expression of IL17 in unstimulated tissues and toxicity attack test results demonstrated that these genes play critical roles under normal conditions and during bacterial infection. | 30342169 | 2019 | ||||
|
0.090 | Biomarker | group | BEFREE | Finally, we examine the implications of IL-17 biology in infectious diseases for the development of novel therapeutic strategies targeted at preventing bacterial infection. | 29345518 | 2018 | ||||
|
0.090 | Biomarker | group | BEFREE | The majority of the up-regulated cytokines are involved in the IL-23/IL-17 cytokine-regulated network, which is crucial for host defense against bacterial infection. | 28899359 | 2017 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Absence of TRIF in macrophages (Mϕs) but not dendritic cells led to a predominant generation of CD4(+) central memory T cells that express IL-17 during enteric bacterial infection in mice. | 26351279 | 2015 | ||||
|
0.090 | Biomarker | group | BEFREE | IL-17A is an important cytokine involved in early immune responses against fungal and bacterial infections, but its role in the response against viral infections is yet to be fully clarified. | 24532300 | 2014 | ||||
|
0.090 | Biomarker | group | BEFREE | As with other bacterial infections, there is considerable interest in characterizing the contribution of interleukin-17A (IL-17A) responses to protective immunity. | 22384827 | 2012 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Relatively low expression of IL-17 may explain the lack of neutrophils in lesions of CTCL, which correlates with bacterial infections that commonly occur in skin affected by CTCL. | 22048239 | 2011 | ||||
|
0.090 | Biomarker | group | BEFREE | Since IL-23 enhances T cell-derived IL-17 during bacterial infections, we then assessed the role of IL-23 in controlling IL-17 expression in Hp-colonized stomach. | 18200634 | 2008 |