Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.030 GeneticVariation disease BEFREE Our study showed that MDR1 genes and their polymorphisms may affect a patient's BD susceptibility and colchicine response. 22705826 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.030 GeneticVariation disease BEFREE We investigated the distribution of MDR1 C3435T polymorphism in 69 patients from the Iranian Azeri Turks group with BD and 92 ethnically sex-matched healthy controls, via the polymerase chain reaction-restriction fragment length polymorphism technique. 24898446 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.030 GeneticVariation disease BEFREE We concluded that ABCB1 C3435T polymorphism is not associated with a colchicine response in patients with Behçet's disease. 21218380 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease LHGDN Angiotensin-converting enzyme I/D polymorphism in Behçet's disease. 15961928 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE As a result of this study, ACE gene I/D polymorphism DD genotype could be a genetic marker in BD in Turkish study population. 23065219 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE A cohort of 90 patients with BD were evaluated for their ACE genotype (male/female: 49/41, mean age: 36.9+/-10.6 years, min/max: 16-66 years). 15045629 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE The distrubition of "DD", "ID" and "II" genotypes of the ACE gene were 32 (43.8%), 29 (39.8%) and 12 (16.4%) for BD patients and 32 (35.5%), 35 (38.9%) and 23 (25.6%) for healthy controls. 19255721 2009
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE An association between Behçet's disease and ACE polymorphism may provide a useful basis for future molecular studies and therapeutic approaches in this complex disease. 15961928 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE Association of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism with BD has been reported in Turkish population. 23455487 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.060 GeneticVariation disease BEFREE This meta-analysis shows that the ACE I/D polymorphism is associated with vasculitis susceptibility, especially in BD and HSP. 22277255 2012
Entrez Id: 47
Gene Symbol: ACLY
ACLY
0.010 AlteredExpression disease BEFREE Therefore, SLC25A1 and ACLY upregulation suggests that metabolic reprogramming in BS involves the citrate pathway dysregulation. 30050389 2018
Entrez Id: 60
Gene Symbol: ACTB
ACTB
0.010 Biomarker disease BEFREE These results suggest that the increase of 42-merP and truncated actin in patients with Behçet's disease changes functions of neutrophils 11456109 2001
Entrez Id: 100
Gene Symbol: ADA
ADA
0.010 AlteredExpression disease BEFREE These associations include ERAP1, CCR1-CCR3, STAT4, KLRC4, GIMAP4, and TNFAIP3 in Behçet's disease; BLK and CD40 in Kawasaki disease; SERPINA1 and SEMA6A in antineutrophil cytoplasmic antibody associated vasculitides; IL12B and FCGR2A/ FCGR2A in Takayasu arteritis; and CECR1 in a newly defined vascular inflammatory syndrome associated with adenosine deaminase (ADA2) deficiency. 25405820 2015
Entrez Id: 51816
Gene Symbol: ADA2
ADA2
0.110 CausalMutation disease CLINVAR
Entrez Id: 51816
Gene Symbol: ADA2
ADA2
0.110 AlteredExpression disease BEFREE These associations include ERAP1, CCR1-CCR3, STAT4, KLRC4, GIMAP4, and TNFAIP3 in Behçet's disease; BLK and CD40 in Kawasaki disease; SERPINA1 and SEMA6A in antineutrophil cytoplasmic antibody associated vasculitides; IL12B and FCGR2A/ FCGR2A in Takayasu arteritis; and CECR1 in a newly defined vascular inflammatory syndrome associated with adenosine deaminase (ADA2) deficiency. 25405820 2015
Entrez Id: 104
Gene Symbol: ADARB1
ADARB1
0.010 AlteredExpression disease LHGDN Serum and erythrocyte adenosine deaminase activities in patients with Behçet's disease. 16961545 2006
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.020 Biomarker disease BEFREE Levels of resistin (SMD = 0.51, 95% CI 0.92-0.918, P = 0.02) and adiponectin (SMD = 0.31, 95% CI 0.06-0.56, P = 0.02) were significantly higher in the BD group after adjustment for age, sex and body mass index (BMI), but not without such adjustment (resistin: (SMD = 0.38, 95% CI -0.18 to 0.93, P = 0.19; adiponectin: SMD = -0.59, 95% CI -2.23 to 1.06, P = 0.48). 29356069 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.020 AlteredExpression disease LHGDN Insulin resistance and adiponectin levels in Behçet's syndrome. 17949565 2008
Entrez Id: 84890
Gene Symbol: ADO
ADO
0.010 Biomarker disease BEFREE Our findings confirmed the association of four loci (<i>LACC1</i>, <i>CEBPB-PTPN1</i>, <i>ADO-EGR2</i> and <i>RIPK2</i>) in Chinese Han patients with BD. 29907633 2018
Entrez Id: 196
Gene Symbol: AHR
AHR
0.320 Biomarker disease CTD_human Further studies are needed to investigate whether modulation of AhR might be used in the treatment of BD. 25045206 2014
Entrez Id: 196
Gene Symbol: AHR
AHR
0.320 AlteredExpression disease BEFREE In this study, we investigated the mRNA expression of AHR in the monocyte-derived and M1 macrophages in active BD patients in comparison to healthy controls. 29149781 2017
Entrez Id: 196
Gene Symbol: AHR
AHR
0.320 Biomarker disease BEFREE Further studies are needed to investigate whether modulation of AhR might be used in the treatment of BD. 25045206 2014
Entrez Id: 57379
Gene Symbol: AICDA
AICDA
0.010 GeneticVariation disease BEFREE Therefore, a high percentage of patients with BD have rare variants in AID genes. 30808881 2019
Entrez Id: 199
Gene Symbol: AIF1
AIF1
0.010 GeneticVariation disease BEFREE In order to identify other genes of susceptibility to BD within the HLA region we investigated the distribution of human Allograft Inflammatory Factor-1 (AIF-1) gene variants among BD patients and healthy controls from Sardinia. 30252881 2018
Entrez Id: 9447
Gene Symbol: AIM2
AIM2
0.010 GeneticVariation disease BEFREE Patients and controls were genotyped and 2 tSNP (rs6940 in IFI16 and rs855873 in AIM2) were associated with BD. 25641891 2015