Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease BEFREE A high number of patients with BD and a considerable number of patients with MDD endorsed several items in the manic section of the mood, energy, and cognition domains, this confirming the centrality of mixed features in patients with mood disorders and the need for a unitary, dimensional, descriptive and dynamic approach to MDD and BD, such as the recently proposed ACE (Activity, Cognition, Energy) model. 31630470 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 AlteredExpression disease BEFREE We observed a positive correlation between Ndel1 activity and the total YMRS score in BD group (p = 0.030) and a positive correlation between ACE activity and Ham-D score (p = 0.047). 30321766 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease BEFREE Using an ACE model, IQ and visual-spatial learning showed statistically significant genetic correlations with bipolar disorder (rg = ;0.51;-;1.00;), which remained significant after covarying for affective symptoms. 26989096 2016
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 GeneticVariation disease BEFREE Meta-analysis of ACE gene I/D polymorphism and bipolar disorder susceptibility. 21314245 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease PSYGENET Meta-analysis of ACE gene I/D polymorphism and bipolar disorder susceptibility. 21314245 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 GeneticVariation disease BEFREE SZ and BD characterized by similar or different gene variant in ACE could be a useful marker for these psychiatric disorders, if this polymorphism is replicated in the future studies. 20010451 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease PSYGENET As SZ and BD have some susceptibility genes in common and since unaffected first-degree relatives of these patients carry a high likelihood of these susceptibility genes, we aimed to elucidate the role of angiotensin-converting enzyme (ACE) genetic variants in patients with SZ, BD and their first-degree relatives. 20010451 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease RGD The genetic association database. 15118671 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 GeneticVariation disease BEFREE We examined the frequency of a functional insertion/deletion (I/D) polymorphism in the 16th intron of the ACE gene (located on chromosome 17q23) in groups of patients with schizophrenia (n = 104 and 113), major depression (n = 55), and bipolar disorder (n = 87) compared to healthy control subjects (n = 87). 11920854 2002
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease PSYGENET In this cross-sectional study, we examined the association between functional polymorphisms in the angiotensin converting enzyme (ACE) and angiotensinogen (AGT) genes in 115 bipolar affective disorder (BPAD) patients and 323healthy control subjects. 11027844 2000
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 GeneticVariation disease BEFREE In this cross-sectional study, we examined the association between functional polymorphisms in the angiotensin converting enzyme (ACE) and angiotensinogen (AGT) genes in 115 bipolar affective disorder (BPAD) patients and 323healthy control subjects. 11027844 2000
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.570 Biomarker disease PSYGENET No significant association was found with bipolar disorder type I or unipolar recurrent depression and the polymorphism of the ACE gene. 11145009 2000