Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 15
Gene Symbol: AANAT
AANAT
0.300 Biomarker disease PSYGENET We assessed the contribution of AANAT gene variability to susceptibility to MD considering common and rare genetic variations through a sequential sequencing and single nucleotide polymorphism (SNP)-based genotyping approach in a sample of 445 unrelated patients with MD (257 unipolar MD, 188 bipolar depression) and 440 community-based screened control subjects. 20459461 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.200 Biomarker disease RGD The genetic association database. 15118671 2004
Entrez Id: 108
Gene Symbol: ADCY2
ADCY2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 1109
Gene Symbol: AKR1C4
AKR1C4
0.300 Biomarker disease CTD_human AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. 21570127 2011
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.300 Biomarker disease CTD_human Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.300 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.010 GeneticVariation disease BEFREE Studies reporting data on the clinimetric validity of the HAM-D6 and either the HAM-D17 or MADRS in non-psychotic unipolar or bipolar depression were included in the synthesis. 28490031 2017
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3
0.200 Biomarker disease MGD
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease BEFREE The effect of childhood trauma on serum BDNF in bipolar depression is modulated by the serotonin promoter genotype. 28754344 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease BEFREE Although no concrete biomarker has been identified for bone disorders in adulthood, reduced brain-derived neurotrophic factor (BDNF) concentrations in cord blood and BDNF DNA methylation might predict schizophrenia and possibly depression, bipolar disorder and autism. 31577039 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease BEFREE In this study, we aimed to investigate the role of mature BDNF (mBDNF) and its precursor (proBDNF) in distinguishing bipolar depression (BP) from MDD during acute depressive episode. 27613282 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.340 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 8553
Gene Symbol: BHLHE40
BHLHE40
0.300 Biomarker disease CTD_human Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles. 25395965 2014
Entrez Id: 80114
Gene Symbol: BICC1
BICC1
0.010 AlteredExpression disease BEFREE Serum BICC1 levels in drug-free patients with MDD (n=30), BM (n=30), and BD (n=13), and well-matched healthy controls (HC, n=30) were measured with ELISA kits. 30697050 2019
Entrez Id: 100128998
Gene Symbol: C20orf181
C20orf181
0.010 AlteredExpression disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 GeneticVariation disease BEFREE Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Ca<sub>v</sub> 1.2, is associated with clinical diagnoses of bipolar disorder, depression and schizophrenia. 28186690 2017
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.310 Biomarker disease CTD_human Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
0.300 Biomarker disease CTD_human Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. 28194001 2017