Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.560 | Biomarker | disease | BEFREE | At this time, little is known about the influence of STAG2 on cellular migration, invasion, proliferation, and cell death, and such studies are required to determine the role of STAG2 in bladder cancer and other malignancies. | 29501732 | 2018 | ||||
|
0.560 | Biomarker | disease | BEFREE | Collectively, these data suggest that STAG2 acts as a tumor suppressor gene in bladder cancer and may be a potential therapeutic target in BC. | 28627627 | 2017 | ||||
|
0.560 | AlteredExpression | disease | BEFREE | Restoration of STAG2 expression in a mutated bladder cancer model alleviates the dependency on STAG1. | 28691904 | 2017 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes. | 24270882 | 2014 | ||||
|
0.560 | Biomarker | disease | CTD_human | Our findings indicate that STAG2 is a new UBC tumor suppressor acting through mechanisms that are different from its role in preventing aneuploidy. | 24121791 | 2013 | ||||
|
0.560 | Biomarker | disease | CTD_human | Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. | 24121792 | 2013 | ||||
|
0.560 | Biomarker | disease | CTD_human | These findings identify STAG2 as one of the most commonly mutated genes in bladder cancer. | 24121789 | 2013 | ||||
|
0.560 | Biomarker | disease | BEFREE | Our findings indicate that STAG2 is a new UBC tumor suppressor acting through mechanisms that are different from its role in preventing aneuploidy. | 24121791 | 2013 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | These findings identify STAG2 as one of the most commonly mutated genes in bladder cancer. | 24121789 | 2013 | ||||
|
0.560 | CausalMutation | disease | CGI |