Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Daily dosing of either non-steroidal anti-inflammatory drugs (NSAIDs) or EGFR inhibitors has been shown to prevent bladder cancer development in a N-butyl-(4-hydroxybutyl)nitrosamine (OH-BBN) induced rat model. 31818850 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE Furthermore, TRIP13 expression was positively correlated with EGFR expression in BCa specimens, and the high expression of both TRIP13 and EGFR predicted poor survival. 31337978 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE About 45% of BC tissues stain for both EGFR and HER2. 30765854 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE In the present study, it is reported that epidermal growth factor receptor ligands induced by the upregulation of vascular endothelial growth factor (VEGF)‑A and VEGF‑C via the VEGF receptor (R)2/nuclear factor‑κB signaling pathway in ECs, may trigger EGFR signaling in bladder cancer cells and promote bladder cancer progression. 30816487 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE These UCNP-AuNR nanoclusters are further functionalized with antibodies to epidermal growth factor receptor (EGFR) to target bladder cancer cells known to overexpress EGFRs. 30678969 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE ERα decreased circ_0023642 levels and subsequently increased miR-490-5p expression, resulting in decreased EGFR expression to suppress BCa cell invasion. 31455760 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Epidermal Growth Factor Receptor-Targeted Multifunctional Photosensitizers for Bladder Cancer Imaging and Photodynamic Therapy. 30776232 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways. 30053908 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE The p53 and EGFR pathways are frequently altered in bladder cancer, yet their contributions to its progression remain elusive. 29440146 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Exploring the roles of urinary HAI-1, EpCAM & EGFR in bladder cancer prognosis & risk stratification. 29861867 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Epidermal Growth Factor Receptor Family Inhibition Identifies P38 Mitogen-activated Protein Kinase as a Potential Therapeutic Target in Bladder Cancer. 29154981 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE In the present study, we aimed to investigate whether EGFR or HER2 may serve as a target for T cell-mediated immunotherapy against human bladder cancer. 29328392 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE These results suggest that high sHER3 levels are associated with improved survival rates in patients with bladder cancer, and that sHER3 inhibits bladder cancer cell growth and migration. 29434875 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE We aimed to investigate the prognostic significance of EGFR expression in patients receiving cisplatin-based adjuvant chemotherapy following radical cystectomy for advanced BC. 30413194 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE The cytotoxicity of <sup>111</sup>In delivered by the EGFR-targeted MNT (<sup>111</sup>In-MNT) was greatly enhanced on EJ-, HT-1376-, and 5637-expressing EGFR bladder cancer cell lines compared with <sup>111</sup>In non-targeted control. 30510514 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE EGFR expression was confirmed to be elevated in six bladder cancer cell lines. 29456764 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE In conclusion, miR-202 suppresses bladder cancer carcinogenesis and progression by targeting EGFR, thereby representing a potential target for miRNA-based therapy for bladder cancer in the future. 29298735 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Epidermal growth factor receptor (EGFr)-targeted therapy may be used in subgroups of patients with urinary bladder cancer. 29508172 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE We performed EGFR immunohistochemistry on 126 cases of bladder cancer and association of EGFR expression with tumor grade, lamina propria invasion, deep muscle invasion and recurrence of disease was evaluated. 29879970 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 Biomarker disease BEFREE Here, a mutation panel of six cancer-associated genes (TSC1, FGFR3, TERT, TP53, PIK3CA and ERBB2) and an immunohistochemistry (IHC) panel containing eight bladder cancer (BC) biomarkers (EGFR, RRM1, PD-L1, BRCA1, TUBB3, ERCC, ERCC1, aberrantly glycosylated integrin α3β1 (AG) and CK5/6) were developed. 29941343 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 GeneticVariation disease BEFREE A total, 50 Moroccan patient specimens with bladder cancer and 48 healthy controls were analysed for EGFR mutations in the region delimiting exons 18-21 by PCR amplification and direct sequencing. 28719349 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell. 28057023 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE EGFR staining of TMAs showed that while most bladder cancers have expression of EGFR to a varying degree, squamous cell carcinomas (SCC) have the highest expression of EGFR. 28619755 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE We conclude that the decreased expression of the tumor-suppressive miR-23b/27b cluster enhanced cancer cell proliferation, migration and invasion in BC through direct regulation of EGFR and c-Met signaling pathways. 25405368 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.400 AlteredExpression disease BEFREE SH3BGRL3 expression is significantly associated with a high level of epidermal growth factor receptor (EGFR) in bladder cancer (P < 0.0001). 26286913 2015