Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer. 26901067 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 Biomarker disease CTD_human Consistent with the aggressive clinical behavior of plasmacytoid carcinomas, which frequently recur locally, CRISPR/Cas9-mediated knockout of CDH1 in bladder cancer cells enhanced cell migration. 26901067 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE Our meta-analysis revealed that the A variant of CDH1 -160C/A polymorphism was associated with an increased risk of bladder cancer. 24491043 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE E-cadherin gene promoter hypermethylation may contribute to the risk of bladder cancer among Asian populations. 24404589 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 Biomarker disease BEFREE Indistinct DNA hypermethylation of CDH1 and SFN genes between tumoral and normal urinary bladder samples suggests that these epigenetic features are not suitable biomarkers for urinary bladder cancer. 18702824 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 Biomarker disease CTD_human Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma. 17520682 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE The purpose of this study is to investigate the association of an E-cadherin promoter polymorphism (CDH1c-160a) with the risk of bladder cancer recurrence. 16922727 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 Biomarker disease RGD E-cadherin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats. 17167984 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE This study supports earlier suggestions that the -160 C/A SNP in the CDH1 promoter is a risk factor for bladder cancer. 16934975 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 AlteredExpression disease BEFREE Normal and bladder cancer samples from 51 patients were compared in terms of E-cadherin gene expression and methylation status by immunohistochemistry, methylation-specific polymerase chain reaction (MSP), and bisulfite genome-sequencing techniques. 12203370 2002
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 PosttranslationalModification disease BEFREE We investigated the possibility that aberrant methylation of the CpG island flanking the 5' transcriptional start site of the e-cadherin gene is responsible for the decreased expression of this gene in bladder cancer, similar to the relationship previously seen between e-cadherin methylation and gene expression in other types of human cancers. 11549575 2001
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 GeneticVariation disease BEFREE These observations, which, nevertheless, need to be confirmed in a larger number of patients, suggest that alterations of E-cadherin gene may be related to pathobiology of bladder cancer development and clinical progression. 10891567 2000
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.690 CausalMutation disease CLINVAR