Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease BEFREE Importin-11 overexpression can promote BCa cell invasiveness, probably associated with the deregulation of CDKN1A and THBS1 primarily through the activation of the proteoglycans in cancer pathway and the classical BCa pathway. 29602637 2018
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease BEFREE To determine the differential protein expression of biomarkers FGFR3, PI3K (subunits PI3Kp110α, PI3KClassIII, PI3Kp85), AKT, p21Waf1/Cip1 and cyclins D1 and D3 in T1 bladder cancer versus healthy tissue and to study their potential role as early recurrence markers. 27726892 2017
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease BEFREE We used lentivirus-mediated short hairpin RNA to knock down p21/Waf-1 in two bladder cancer cell lines EJ and 5637. 27622605 2017
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 GeneticVariation disease BEFREE Our findings suggest that TP53/CDKN1A double-mutant bladder cancer cells have a unique dependence on Chk1 activity for the G2-M cell-cycle checkpoint in response to chemotherapy-induced DNA damage. 25349305 2015
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 AlteredExpression disease BEFREE Clinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in bladder cancer. 26191193 2015
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease CTD_human Polymorphisms in cell cycle regulatory genes, urinary arsenic profile and urothelial carcinoma. 18640142 2008
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 AlteredExpression disease LHGDN Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase. 17671727 2007
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 AlteredExpression disease LHGDN Association of p53 and p21 expression with clinical outcome in patients with carcinoma in situ of the urinary bladder. 12809883 2003
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 GeneticVariation disease LHGDN p21 gene codon 31 polymorphism is associated with bladder cancer. 12474524 2002
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease BEFREE Here we investigated the effect of ADM on cell cycle progression and expression of cell cycle regulating proteins in bladder cancer cell lines with various p53 and p21(WAF1/CIP1) status. 11277327 2000
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 Biomarker disease BEFREE To evaluate whether p21 (WAF-1/CIP1) should be considered a potential candidate for human bladder cancer gene therapy, we determined: (1) the basal level of p21 expression in bladder cancer cell lines, (2) the response of bladder cancer cells to increased p21 expression following p21 adenovirus infection, and (3) the mechanism of growth inhibition produced by p21 overexpression. 10688044 2000
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 AlteredExpression disease BEFREE Correlation and prognostic significance of p53, p21WAF1/CIP1 and Ki-67 expression in patients with superficial bladder tumors treated with bacillus Calmette-Guerin intravesical therapy. 10022686 1999
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 AlteredExpression disease BEFREE Although a potential tumor suppressor gene, WAF1/p21 is expressed in bladder cancer. 9472102 1998
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.400 GeneticVariation disease BEFREE In order to assess potential p21WAF1/CIP1 gene alterations in human bladder cancer, we have examined this gene and its encoded product in a well-characterized cohort of 27 primary bladder tumors. 9114433 1996