×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
BEFREE
At this time, little is known about the influence of STAG2 on cellular migration, invasion, proliferation, and cell death, and such studies are required to determine the role of STAG2 in bladder cancer and other malignancies.
29501732
2018
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
AlteredExpression
disease
BEFREE
Restoration of STAG2 expression in a mutated bladder cancer model alleviates the dependency on STAG1.
28691904
2017
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
BEFREE
Collectively, these data suggest that STAG2 acts as a tumor suppressor gene in bladder cancer and may be a potential therapeutic target in BC.
28627627
2017
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
AlteredExpression
disease
BEFREE
STAG2 mRNA in normal bladder cells and bladder tumor cells was evaluated by RT-PCR.
25867412
2015
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
GeneticVariation
disease
BEFREE
Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes.
24270882
2014
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
CTD_human
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation.
24121792
2013
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
BEFREE
Our findings indicate that STAG2 is a new UBC tumor suppressor acting through mechanisms that are different from its role in preventing aneuploidy.
24121791
2013
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
CTD_human
These findings identify STAG2 as one of the most commonly mutated genes in bladder cancer .
24121789
2013
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
Biomarker
disease
CTD_human
Our findings indicate that STAG2 is a new UBC tumor suppressor acting through mechanisms that are different from its role in preventing aneuploidy.
24121791
2013
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
GeneticVariation
disease
BEFREE
These findings identify STAG2 as one of the most commonly mutated genes in bladder cancer .
24121789
2013
×
Entrez Id:
10735
Gene Symbol:
STAG2
STAG2
0.570
CausalMutation
disease
CGI