Gene: NFKB1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.330 GeneticVariation disease BEFREE IκBKβ's rs6474387 (C>T intron 20) and rs11986055 (A>C intron 2) showed substantially lower colon cancer risk among current NSAID users (P(interaction) = 0.01 and P(interaction) = 0.045, respectively), whereas NFκB1's rs230490 (G>A 5' (outside UTR)) and rs997476 (C>A 3' (outside UTR)) showed higher CRC risk among current NSAID users (P(interaction) = 0.01 and P(interaction) = 0.03, respectively). 23002237 2013
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.330 Biomarker disease CTD_human NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). 20715105 2011
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.330 GeneticVariation disease BEFREE The most significant finding (nominal P = 0.0004; false discovery rate q = 0.037) was a combined genotype association across IKBKB SNP rs5029748 (1 or 2 variant alleles), IL6 rs1800797 (1 or 2 variant alleles), and NFKB1 rs4648110 (2 variant alleles) which conferred an ~80% decreased risk of colon cancer. 21129206 2010
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.330 Biomarker disease CTD_human Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats. 19028472 2009
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.330 AlteredExpression disease BEFREE Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50. 19509257 2009