×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Are XPD and XPG gene variants related to the mechanism of oral squamous cell carcinoma ?
30672443
2018
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
Biomarker
disease
BEFREE
For ERCC2 Gln751Gln, the association was significant for both SCC s (P=0.001, OR=10.1, 95% CI=2.6-37.9) and SILs (P=0.001, OR=8.9, 95% CI=2.8-28.3).
25812040
2016
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Association of the XPD and XRCC3 gene polymorphisms with oral squamous cell carcinoma in a Northeastern Brazilian population: A pilot study.
26742000
2016
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Polymorphisms in ERCC2/XPD Asp312Asn may be associated with increased DNA adduct levels in the lung, especially among subjects with SQCC .
26001533
2015
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Both of CCNH-V270A C/C or C/T and XPD 751 A/A showed a significant longer survival in the squamous cell carcinoma subgroup (P=0.047 and P=0.034 respectively).
21676483
2012
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2 ) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population.
19615095
2009
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
LHGDN
Similarly, XPD Asn312Asn (AA) reduced the risk of cervical or cervical squamous cell carcinoma .
19096231
2008
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
Biomarker
disease
CTD_human
Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire.
17687452
2007
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
AlteredExpression
disease
LHGDN
Reduced expression of human DNA repair genes in esophageal squamous-cell carcinoma in china.
17479411
2007
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
LHGDN
XRCC1 codon 399 and ERCC2 codon 751 polymorphism, smoking, and drinking and risk of esophageal squamous cell carcinoma in a North Indian population.
17556064
2007
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
Accumulation of certain alleles or genotypes of the CYP1A1, NAT2, GSTM1 and XPD seems to be associated with either increased or decreased risk to develop laryngeal SCC .
15914211
2005
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
LHGDN
Polymorphisms in the DNA repair gene XPD and susceptibility to esophageal squamous cell carcinoma.
15381366
2004
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
Biomarker
disease
BEFREE
Combinations of polymorphisms in genes involved in the same repair pathway (XPA + XPD or XRCC1 + APE1) affected lung cancer risk only in patients with SCC .
15333465
2004
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
LHGDN
[Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing].
12579497
2003
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
LHGDN
Polymorphisms of DNA repair genes XRCC1 and XPD and their associations with risk of esophageal squamous cell carcinoma in a Chinese population.
12124811
2002
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
GeneticVariation
disease
BEFREE
These data suggest that the two polymorphisms in the XPD gene may influence risk of smoking-related SCC of the lung.
12399122
2002
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
Biomarker
disease
HPO
×
Entrez Id:
2068
Gene Symbol:
ERCC2
ERCC2
0.700
CausalMutation
disease
CGI