Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Are XPD and XPG gene variants related to the mechanism of oral squamous cell carcinoma? 30672443 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 Biomarker disease BEFREE For ERCC2 Gln751Gln, the association was significant for both SCCs (P=0.001, OR=10.1, 95% CI=2.6-37.9) and SILs (P=0.001, OR=8.9, 95% CI=2.8-28.3). 25812040 2016
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Association of the XPD and XRCC3 gene polymorphisms with oral squamous cell carcinoma in a Northeastern Brazilian population: A pilot study. 26742000 2016
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Polymorphisms in ERCC2/XPD Asp312Asn may be associated with increased DNA adduct levels in the lung, especially among subjects with SQCC. 26001533 2015
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Both of CCNH-V270A C/C or C/T and XPD 751 A/A showed a significant longer survival in the squamous cell carcinoma subgroup (P=0.047 and P=0.034 respectively). 21676483 2012
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population. 19615095 2009
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease LHGDN Similarly, XPD Asn312Asn (AA) reduced the risk of cervical or cervical squamous cell carcinoma. 19096231 2008
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 Biomarker disease CTD_human Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire. 17687452 2007
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 AlteredExpression disease LHGDN Reduced expression of human DNA repair genes in esophageal squamous-cell carcinoma in china. 17479411 2007
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease LHGDN XRCC1 codon 399 and ERCC2 codon 751 polymorphism, smoking, and drinking and risk of esophageal squamous cell carcinoma in a North Indian population. 17556064 2007
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE Accumulation of certain alleles or genotypes of the CYP1A1, NAT2, GSTM1 and XPD seems to be associated with either increased or decreased risk to develop laryngeal SCC. 15914211 2005
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease LHGDN Polymorphisms in the DNA repair gene XPD and susceptibility to esophageal squamous cell carcinoma. 15381366 2004
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 Biomarker disease BEFREE Combinations of polymorphisms in genes involved in the same repair pathway (XPA + XPD or XRCC1 + APE1) affected lung cancer risk only in patients with SCC. 15333465 2004
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease LHGDN [Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing]. 12579497 2003
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease LHGDN Polymorphisms of DNA repair genes XRCC1 and XPD and their associations with risk of esophageal squamous cell carcinoma in a Chinese population. 12124811 2002
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 GeneticVariation disease BEFREE These data suggest that the two polymorphisms in the XPD gene may influence risk of smoking-related SCC of the lung. 12399122 2002
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 Biomarker disease HPO
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
0.700 CausalMutation disease CGI