Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group BEFREE Mutations in genes encoding cardiac troponin I (TNNI3) and cardiac troponin T (TNNT2) caused altered troponin protein stoichiometry in patients with dilated cardiomyopathy. 28436080 2018
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 CausalMutation group CLINVAR Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples. 27532257 2017
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 CausalMutation group CLINVAR The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing. 24503780 2015
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 CausalMutation group CLINVAR A systematic approach to assessing the clinical significance of genetic variants. 24033266 2013
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group BEFREE Employing LC-MS/MS, we determined the presence of phosphorylation sites at S5/S6 in cTnI from wild type mouse hearts as well as in hearts of mice chronically expressing active protein kinase C-ε (PKCε) and exhibiting severe dilated cardiomyopathy (DCM). 22940544 2013
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 GeneticVariation group CLINVAR Genetic testing for dilated cardiomyopathy in clinical practice. 22464770 2012
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 CausalMutation group CLINVAR Genetic testing for dilated cardiomyopathy in clinical practice. 22464770 2012
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group BEFREE Furthermore, we demonstrated that splicing of 4 key sarcomere genes, cardiac troponin T (TNNT2), cardiac troponin I (TNNI3), myosin heavy chain 7 (MYH7), and filamin C, gamma (FLNC), was significantly altered in ischemic cardiomyopathy and in dilated cardiomyopathy and aortic stenosis. 20124440 2010
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 GeneticVariation group BEFREE Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy. 19590045 2009
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 GeneticVariation group BEFREE We used mutation analysis suitable for identification of both dominant and recessive mutations to investigate the sarcomeric gene for cardiac troponin I (TNNI3) in 235 patients with dilated cardiomyopathy. 15070570 2004
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group BEFREE Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. 14595408 2004
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group CTD_human We used mutation analysis suitable for identification of both dominant and recessive mutations to investigate the sarcomeric gene for cardiac troponin I (TNNI3) in 235 patients with dilated cardiomyopathy. 15070570 2004
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group GENOMICS_ENGLAND
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.660 Biomarker group HPO