Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Abnormally high serum levels of Lp(a) in patients with CVD and VD seemed to be due to specific increases in low-molecular-weight apolipoprotein(a) isoforms in Lp(a). 10765043 2000
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein (a) and 10-year Cardiovascular Disease Incidence in Apparently Healthy Individuals: A Sex-based Sensitivity Analysis from ATTICA Cohort Study. 31185726 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Several lipoprotein(a)-lowering therapies are currently being developed with the long-term goal of reducing cardiovascular disease and mortality; however, the relationship between lipoprotein(a) and mortality is unclear. 30608559 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 AlteredExpression group BEFREE The purpose of this study was to investigate CHD or cardiovascular disease (CVD) risk scores with cholesterol levels of six fractionated lipoprotein classes {high-density lipoprotein [HDL], low-density lipoprotein [LDL], IDL, VLDL, CM including CM remnant, and lipoprotein (a) [Lp (a)]} in Japanese healthy men. 28025448 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE In this regard, the greater CVD in Blacks than Whites have been partly attributed to other non-traditional CVD risk factors, such as subclinical inflammation (C-reactive protein), homocysteine, increased low-density lipoprotein oxidation, lipoprotein a, adiponectin, and plasminogen activator inhibitor-1, etc. 28912752 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE New and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), and triglyceride-rich lipoproteins are concordant with both the magnitude and direction of the expected risk of cardiovascular disease, whereas this is unclear for HDL cholesterol. 21358543 2011
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein(a) as a key target in combined therapeutic approaches for cardiovascular disease. 31530423 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group CTD_human Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy. 18775538 2009
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein(a) [Lp(a)] has been considered to be a predictor of premature coronary heart disease and other cardiovascular diseases. 10098351 1999
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE To examine the relations between genetic loci, plasma lipoprotein(a) [Lp(a)] levels, and cardiovascular disease (CVD) risk among diabetic patients and compare with the observations in the general population. 21900290 2012
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Increased levels of lipoprotein (a) [Lp(a)] have been considered an independent risk factor for cardiovascular disease, but the mechanism behind this relationship is not completely understood. 9580386 1998
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE 1.Elevated plasma lipoprotein (a) (Lp(a)) concentrations have been correlated with an increased risk of premature cardiovascular disease. 10225140 1999
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Robust epidemiologic and genetic studies have solidified the role of lipoprotein (a) [Lp(a)] as an independent and causal risk factor for cardiovascular disease. 25736345 2015
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE High lipoprotein(a) (Lp(a)) serum concentrations and the underlying apolipoprotein(a) (apo(a)) phenotypes are risk factors for cardiovascular disease in the general population as well as in patients with renal disease. 10616846 2000
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Elevated low-density lipoprotein cholesterol and/or lipoprotein(a) are established risk factors for cardiovascular disease (CVD). 30799420 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein(a) (Lp[a]) is proatherosclerotic and prothrombotic, causally related to coronary disease, and associated with other cardiovascular diseases. 29246963 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE The objective was to investigate the effects of isolated soy isoflavones on metabolic biomarkers of cardiovascular disease risk, including plasma total, HDL, and LDL cholesterol; triacylglycerols; lipoprotein(a); the percentage of small dense LDL; glucose; nonesterified fatty acids; insulin; and the homeostasis model assessment of insulin resistance. 16522905 2006
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein(a) in American Indians is low and not independently associated with cardiovascular disease. The Strong Heart Study. 11880218 2002
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Although lipoprotein(a) [Lp(a)] is associated with incident cardiovascular disease (CVD), its contribution to prediction remains controversial. 30012322 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: recent advances and future directions. 14578310 2003
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Family history of early cardiovascular disease in children with moderate to severe hypercholesterolemia: relationship to lipoprotein (a) and low-density lipoprotein cholesterol levels. 10072255 1999
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Increased plasma level of lipoprotein(a) (Lpa) is a risk factor of cardiovascular diseases. 30071823 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group BEFREE Therefore, in the evaluation of a fully automated, particle-enhanced turbidimetric immunoassay for the measurement of lipoprotein(a) we have determined its reference interval in the Spanish population, an area with the lowest incidence of cardiovascular disease in Europe. 12633762 2003
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 GeneticVariation group LHGDN ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties. 17683612 2007
Entrez Id: 4018
Gene Symbol: LPA
LPA
0.500 Biomarker group BEFREE Lipoprotein(a) [Lp(a)] is an independent CVD risk factor where plasma levels are determined by the apolipoprotein(a) [apo(a)] gene, which contains inflammatory response elements. 18252779 2008