Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 GeneticVariation group BEFREE Both lower and higher MCP-1 levels are associated with an increased risk of all-cause and CVD mortality among CAD patients. 25786118 2016
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group BEFREE Obesity is associated with elevated monocyte chemoattractant protein-1 (MCP-1), a proinflammatory chemokine related to diabetes and cardiovascular disease. 25994074 2016
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group BEFREE These results demonstrate that MCPIP may be an important regulator of inflammatory angiogenesis and provide novel mechanistic insights into the link between MCP-1 and cardiovascular diseases. 24008336 2013
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group BEFREE In conclusion, anti-inflammatory gene therapy targeting MCP-1/CCR2 signal, with a novel NP-mediated gene delivery system, is a potent therapeutic strategy for the treatment of cardiovascular diseases. 22023473 2012
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group BEFREE Monocyte chemoattractant protein-1 (MCP-1) is a potent chemokine and plays an important role in cardiovascular diseases. 19781803 2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 GeneticVariation group LHGDN demonstrate for the first time an association between the polymorphism in the regulatory region of the MCP-1 gene and susceptibility to cardiovascular disease in hemodialyzed patients 19014891 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 GeneticVariation group BEFREE Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for cardiovascular disease in hemodialyzed patients. 19014891 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 AlteredExpression group BEFREE We measured CRP (by immunonephelometry) and monocyte expression of TF and MCP-1 (by real-time PCR) in 80 untreated hypertensive patients without clinical cardiovascular disease (CVD) or additional risk factors for CVD compared with 41 controls. 18339698 2008
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 AlteredExpression group BEFREE Thus the augmented MCP-1 expression by ANG II in preadipocytes may provide a new link between obesity and cardiovascular disease. 16705055 2006
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group CTD_human Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production. 16332659 2006
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group LHGDN new role of MCP-1 as an arteriogenic factor in hemodialysis patients with cardiovascular disease. 15627719 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.400 Biomarker group BEFREE Multivariate analyses on 64 study subjects of varying arsenic exposure levels showed that the association of CCL2/MCP1 plasma protein level with blood arsenic remained significant after adjustment for other risk factors of cardiovascular diseases. 12928151 2004