Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 GeneticVariation group GWASCAT Genome-wide association study of colorectal cancer in Hispanics. 27207650 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Therapeutic group RGD Angiostatic properties of sulindac and celecoxib in the experimentally induced inflammatory colorectal cancer. 23149858 2013
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group BEFREE Herein we show that MMP-2 is up-regulated in resected colorectal tumors and degrades β1 integrins with the release of fragments containing the β1 I-domain. 22898815 2012
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group CTD_human Genomic and epigenomic integration identifies a prognostic signature in colon cancer. 21278247 2011
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group BEFREE The high expressions of MMP2 and MMP9 were closely associated with invasion and migration of colorectal tumors and cell lines. 20191032 2010
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group LHGDN Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer. 18425389 2008
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group CTD_human Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. 18507500 2008
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group LHGDN MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not. 18506186 2008
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 GeneticVariation group LHGDN Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese. 17546628 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group LHGDN Prognostic significance of expression of matrix metalloproteinase in colorectal adenocarcinomas and their metastases. 18214299 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group BEFREE Matrix metalloproteinase (MMP)-7 (matrilysin-1) plays significant roles in the growth, invasion, and metastasis of colorectal tumors, while (-)-epigallocatechin-3-gallate (EGCG), a green tea polyphenol with chemopreventive properties, has been shown to be an inhibitor of MMP-2 and MMP-9. 15860507 2005
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 GeneticVariation group LHGDN A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer. 15485653 2004
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group LHGDN Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells. 14666611 2003
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group LHGDN Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients. 14520690 2003
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 Biomarker group BEFREE Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium. 12184536 2002
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group BEFREE We evaluated levels and activity of gelatinase A (MMP-2) and gelatinase B (MMP-9), as well as stromelysin-1 (MMP-3) expression in 101 sporadic colorectal tumors in consideration of the microsatellite instability (MSI) status of the groups. 12097300 2002
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.700 AlteredExpression group BEFREE Matrilysin and gelatinase A, B mRNA expressions were examined in colorectal tumors. 8913260 1996